Single-Nucleotide Polymorphisms in Calpastatin (CAST) and Micro-Calpain (CAPN1) Genes Influencing Meat Tenderness in Crossbred Beef Cattle in Thailand [PDF]
Veterinary SciencesThis study investigated single-nucleotide polymorphisms (SNPs) within the CAPN1 316, CAPN1 4751, and CAST 2959 markers using high-resolution melting (HRM) analysis to predict meat tenderness in crossbred beef cattle.
Thanathip Thaloengsakdadech +4 more
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Role of Calpains in Uremia-Related Functional and Structural Muscle Changes: Protective Effect of Calpastatin Overexpression [PDF]
CellsSarcopenia, the progressive loss of muscle mass and strength, is a common complication in patients with chronic kidney disease (CKD). This condition arises from a combination of factors including reduced physical activity, insufficient protein intake ...
Elena Gutiérrez-Calabrés +11 more
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Expression of calpastatin hcast 3-25 and activity of the calpain/calpastatin system in human glioblastoma stem cells: possible involvement of hcast 3-25 in cell differentiation [PDF]
Frontiers in Molecular BiosciencesGlioblastoma (GBM) is the most malignant brain tumor, characterized by cell heterogeneity comprising stem cells (GSCs) responsible for aggressiveness. The calpain/calpastatin (calp/cast) proteolytic system is involved in critical physiological processes ...
Sonia Spinelli +10 more
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Different Proteins as Biomarkers for Sac Shrinkage After Endovascular Aortic Repair of Abdominal Aortic Aneurysms [PDF]
Journal of Cardiovascular Development and DiseaseBackground: This study aims to identify circulating biomarkers by using proteomic analysis associated with sac shrinkage or expansion in patients undergoing endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAAs).
Alexander Zimmermann +6 more
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Calpastatin (CAST) Gene Polymorphism in Tsigai and Merinoland Sheep Breeds Under Conditions of the Republic of Crimea [PDF]
BIO Web of Conferences, 2021 The article presents the results of studying the Calpastatin (CAST) gene polymorphism in Tsigai (n = 23) and Merinoland sheep breed (n = 13). The purpose of the research.
Uppe Veronika +4 more
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Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of Excitable Bos taurus indicus Cattle [PDF]
MetabolitesBackground: Bos taurus indicus cattle is known to be temperamental and to produce beef with greater variability in terms of quality compared to beef of Bos taurus taurus.
Patricia Maloso Ramos +8 more
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Phosphorylation of Calpastatin Negatively Regulates the Activity of Calpain
Life, 2023 Tenderness is an important characteristic of meat quality. Calpastatin and calpain play important roles in meat tenderization. However, it is not clear how phosphorylation affects the regulation of calpastatin on μ-calpain and, consequently, meat ...
Yuqiang Bai +6 more
doaj +1 more source
Expression of calpastatin gene in Raini Cashmere goat using Real Time PCR [PDF]
مجله بیوتکنولوژی کشاورزی, 2020 Objective Calpastatin has been found in skeletal muscle tissue of animals and could prevent unrestrained cellular growth by suppressing calpain activity. The involvement of calpains in apoptosis has been a subject of debate, although their involvement is
Mohammadreza Mohammadabadi
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Different nutritional systems influence the tenderness and lipid oxidation of ewe lamb meat without altering gene expression [PDF]
Anais da Academia Brasileira de Ciências, 2023 Feeding is a determining factor in the various characteristics of sheep meat and animal performance, the objectives were to evaluate the effect of supplementation of ewe lambs finished in different nutritional planes on the gene expression of CASP3 ...
ISABELLA G. SILVA +8 more
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Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals. [PDF]
PLoS ONE, 2011 Calpain, a calcium-dependent cysteine protease, is reportedly involved in the pathophysiology of autoimmune diseases such as rheumatoid arthritis (RA).
Mikiko Iguchi-Hashimoto +13 more
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