Results 31 to 40 of about 2,875 (178)

Activation of Calpain Contributes to Mechanical Ventilation-Induced Depression of Protein Synthesis in Diaphragm Muscle

open access: yesCells, 2022
Mechanical ventilation (MV) is a clinical tool that provides respiratory support to patients unable to maintain adequate alveolar ventilation on their own.
Hayden W. Hyatt   +3 more
doaj   +1 more source

Effect of postmortem storage on shear force value and calpain/calpastatin activity in longissimus dorsi muscle of rusa deer (cervus timorensis) [PDF]

open access: yesMATEC Web of Conferences, 2018
The objective of this study was to determine the effects of aging period on shear force values and activities of calpain/calpastatin enzymes of the longissimus dorsi (LD) muscle from rusa deer (Cervus timorensis).
Jantasaeng Orapin   +2 more
doaj   +1 more source

Polymorphism of Genes and Their Impact on Beef Quality

open access: yesCurrent Issues in Molecular Biology, 2023
The single-nucleotide polymorphism (SNP) form of genes is a valuable source of information regarding their suitability for use as specific markers of desirable traits in beef cattle breeding.
Piotr Kostusiak   +4 more
doaj   +1 more source

Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway

open access: yesFrontiers in Cellular Neuroscience, 2018
The purpose of the current study was to investigate whether peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) can interact with calpastatin (CAST) and regulate CAST/calpain2, under excessive glutamate conditions, and subsequently regulate ...
Shuchao Wang   +12 more
doaj   +1 more source

The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma. [PDF]

open access: yesPLoS ONE, 2013
Conventional calpains are ubiquitous cysteine proteases whose activity is promoted by calcium signaling and specifically limited by calpastatin. Calpain expression has been shown to be increased in human malignant cells, but the contribution of the ...
Quentin Raimbourg   +7 more
doaj   +1 more source

Polymorphism of the ovine calpastatin gene

open access: yesMolecular and Cellular Probes, 2007
Calpastatin is a specific inhibitor of calpains and has been implicated in the regulation of beef tenderization. Variation in the ovine calpastatin gene (CAST) was investigated by amplification of a fragment containing the entire exon 6 using polymerase chain reaction (PCR), followed by single-strand conformational polymorphism (PCR-SSCP) analysis and ...
H, Zhou, J G H, Hickford, H, Gong
openaire   +2 more sources

Influence of vitamins A, D3 and E status on post-mortem meat quality in steers under winter housing or pasture finishing systems

open access: yesAnimal, 2011
We investigated the influence of Swedish recommended vitamins A, D3 and E supplementation levels on muscle tenderness and fatty acid (FA) composition under indoor or outdoor finishing programmes.
T. Turner   +6 more
doaj   +1 more source

Calpastatin participates in the regulation of cell migration in BAP1-deficient uveal melanoma cells [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To detect how BRCA-associated protein 1 (BAP1) regulates cell migration in uveal melanoma (UM) cells. METHODS: Wound healing and transwell assays were performed to detect UM cell migration abilities.
Han Yue   +5 more
doaj   +1 more source

Binding of calpain fragments to calpastatin

open access: yesJournal of Biological Chemistry, 1991
Their cDNA-derived amino acid sequences predict that the 80-kDa subunits of the micromolar and millimolar Ca(2+)-requiring forms of the Ca(2+)-dependent proteinase (mu- and m-calpain, respectively) each consist of four domains and that the 28-kDa subunit common to both mu- and m-calpain consists of two domains.
T, Nishimura, D E, Goll
openaire   +2 more sources

Study on genetic structure of CAST gene by PCR- SSCP method and its association with growth traits in lori-Bakhtiari sheep breed [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2014
In this study, a 254 bp fragment containing exon 6 and a part of introns 5 and 6 of ovine CAST gene were amplified in 169 Lori-Bakhtiari lamb from Lori-Bakhtiari sheep breeding station by polymerase chain reactions.
Mohsen Ali   +3 more
doaj   +1 more source

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