Results 211 to 220 of about 30,178 (280)
This prospective single‐arm study evaluated neoadjuvant disitamab vedotin plus penpulimab in 20 patients with Stage II–III HER2‐low breast cancer. The regimen showed preliminary activity (pCR 20.0% intention‐to‐treat, 25.0% evaluable; ORR 56.3%) with manageable toxicity.
Xiaoxiao Liu +17 more
wiley +1 more source
EGFR-targeted photoimmunotherapy and its association with the immune microenvironment in locoregional recurrent head and neck squamous cell carcinoma. [PDF]
Yoshizawa K +18 more
europepmc +1 more source
Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng +7 more
wiley +1 more source
Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies. [PDF]
Meyerhoff RR +25 more
europepmc +1 more source
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo +3 more
wiley +1 more source
Reprogramming the immunosuppressive microenvironment in MSS/pMMR colorectal cancer via synergistic pyroptosis induction and PD-L1 suppression. [PDF]
Mo J, Huang W, Li R, Xie Y, Chang L.
europepmc +1 more source
Engineering Photothermal Nanoplatforms for Multimodal Theranostics and Biosensing
ABSTRACT Photothermal platforms bridge materials science and biomedicine, emerging as a transformative frontier in biomedical applications. They offer spatiotemporally precise, noninvasive modalities with cell‐type‐independent efficacy for treating a range of diseases.
Xiao Han +3 more
wiley +1 more source
Self-Assembled Cationic Phthalocyanine Nanophotosensitizer Drives Hypoxia-Tolerant Photodynamic Immunotherapy for HCC. [PDF]
Jiang FC +9 more
europepmc +1 more source
ABSTRACT Calcium overload‐induced immunogenic cell death (ICD) holds great potential in antitumor immunotherapy, and it is a critical strategy for regulating multiple intracellular Ca2+ channels through inhibiting the endogenous Ca2+ efflux and promoting the exogenous Ca2+ influx.
Xingguo Xu +9 more
wiley +1 more source

