Results 221 to 230 of about 28,252 (277)

Combining Tumor Treating Fields with Immunotherapy in Pancreatic Ductal Adenocarcinoma: Mechanisms, Preclinical Evidence, and Emerging Therapeutic Synergy. [PDF]

Cells
Albelal D, Rachamala HK, Saha I, Bhattacharya S, Mukhopadhyay D, Babiker HM.   +5 more
europepmc   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

Cancer Science, Volume 117, Issue 7, Page 2007-2020, July 2026.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan, Ruikang Liu, Fangying Shao, Zheqi Cai, Yingfei Fang, Kan Chen, Yanrong Zhou, Ting Ye, Gongchu Li   +8 more
wiley   +1 more source

Mutant calreticulin-Cancer driver and Achilles' heel for ET? [PDF]

Hemasphere
Reichert M, Psaila B.
europepmc   +1 more source

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

Cell Proliferation, Volume 59, Issue 7, July 2026.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang, Miao Xu, Yongshun Wang, Xuan Lin, Qiang Zhang, Xiaoning Lin, Xin Wu, Cheng Zhang, Wenhua Huang, Jianlin Shen   +9 more
wiley   +1 more source

Lyophilized bacteria-infected tumor cells for targeted immunotherapy of lung metastases and associated fibrosis. [PDF]

Bioact Mater
Chen M, Deng Y, Fang T, Luo T, Chen G.
europepmc   +1 more source

CRISPR/Cas‐Mediated Gene Editing in Plant Immunity and Its Potential for the Future Development of Fungal, Oomycete, and Bacterial Pathogen‐Resistant Pulse Crops

Plant, Cell &Environment, Volume 49, Issue 7, Page 3573-3585, July 2026.
ABSTRACT Pulses provide myriad health benefits and are advantageous in an environmental context as a result of their leguminous nature. However, phytopathogenic fungi, oomycetes and bacteria pose a substantial threat to pulse production, at times leading to crop failure.
Stacy D. Singer, Mohammed M. Mukthar, Udaya Subedi, Hari Poudel, Guanqun Chen, Nora Foroud, Syama Chatterton   +6 more
wiley   +1 more source

Induction of immunogenic necroptosis by shikonin in drug‑resistant head and neck squamous cell carcinoma cells. [PDF]

Oncol Rep
Kishita S, Umemura N, Miyazaki H, Adachi M, Yagi H, Ohkoshi E.   +5 more
europepmc   +1 more source

Crizotinib- or Ceritinib-Conjugated Platinum(IV) Prodrugs As Potent Multiaction Agents Inducing Antiproliferative Effects in 2D and 3D Cancer Cell Models. [PDF]

J Med Chem
Sharkawy S, Acharya S, Kostrhunová H, Maji M, Marková L, Novohradský V, Gibson D, Brabec V.   +7 more
europepmc   +1 more source

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab-paclitaxel. [PDF]

Int J Cancer
Kan T, Haj Khalil T, Barsheshet Y, Voloshin T, Koren L, Koltun B, David C, Wainer-Katsir K, Vorontsova A, Brant B, Zisman-Rozen S, Ene HM, Frechtel-Gerzi R, Cahal S, Klein-Goldberg A, Lifshitz L, Zemer Tov E, Shai M, Haber A, Giladi M, Weinberg U, Palti Y.   +21 more
europepmc   +1 more source

Synthetic zipper mediated pre-targeting system for near-infrared photoimmunotherapy. [PDF]

iScience
Mohiuddin TM, Zhang C, Sheng W, Al-Rawe M, El-Merhie N, Zeppernick F, Meinhold-Heerlein I, Hussain AF.   +7 more
europepmc   +1 more source