Attitudes toward the use of complementary and alternative medicine in children with gastrointestinal symptoms, a multicenter survey study among parents and pediatricians. [PDF]
Bloem MN +9 more
europepmc +1 more source
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang +14 more
wiley +1 more source
Functional Calmodulin States Are Selected from an Electrostatically Tuned Free Energy Landscape. [PDF]
Tayhan B +3 more
europepmc +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
Mechanical Performance of Milled CAD/CAM Versus 3D-Printed Dental Prostheses: A Systematic Review and Meta-Analysis of Flexural Strength and Fracture Resistance. [PDF]
Chauca-Bajaña L +8 more
europepmc +1 more source
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen +7 more
wiley +1 more source
Effects of Computer Assisted Design-Computer Assisted Manufacturing Nickel-Titanium Fixed Lingual Retainers Versus Conventional Flexible Multistrand Retainers on Tooth Displacements and Periodontal Ligament Stress Distributions in the Mandibular Anterior Teeth at Four Different Inclinations: A Finite Element Analysis. [PDF]
Daryanavard H +6 more
europepmc +1 more source
Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti +17 more
wiley +1 more source
Diagnosis, care pathways, and Complementary and Alternative Medicine (CAM) use among digestive cancer patients in Benin: a qualitative study. [PDF]
Merabtine T +9 more
europepmc +1 more source

