Results 111 to 120 of about 19,486 (229)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun   +19 more
wiley   +1 more source

ASIP Variants in Livestock: It's Not Black and White

open access: yesAnimal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Fur and feather pigmentation play an important role in the survival and reproduction of many species, as well as in selective breeding and agriculture. The synthesis of pigment molecules, eumelanin and pheomelanin, is partially regulated by the agouti signalling protein (ASIP) encoded by the ASIP gene.
Isabella M. Brown, Kylie A. Munyard
wiley   +1 more source

Islamic Principles in Western Mental Health: An Interpretative Phenomenological Analysis of Practitioner Perspectives on Integration, Conflict and Harmony

open access: yesCounselling and Psychotherapy Research, Volume 26, Issue 2, June 2026.
ABSTRACT Aims This study explored how UK‐based mental health practitioners (MHPs) understand and integrate Islamic principles into therapeutic work with Muslim clients. Responding to the growing recognition of the cultural and spiritual needs of Muslim populations, the study examined how integration unfolds in practice and its implications for ...
Yusuf Mahmood   +1 more
wiley   +1 more source

DL‐3‐n‐Butylphthalide Protects Against PrP106−126‐Induced Neurotoxicity Through NRF2 Signaling and OPA1/DRP1‐Mediated Mitochondrial Dynamics

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
NBP counteracts PrP106‐126‐induced neurotoxicity by activating NRF2 and restoring OPA1/DRP1‐mediated mitochondrial dynamics. It suppresses oxidative stress and preserves mitochondrial function and bioenergetics. These actions support NBP as a promising therapeutic candidate for prion‐related neurodegeneration.
Wei Wu   +3 more
wiley   +1 more source

Ensemble Modeling Reveals Severe Contraction of Dhole's (Cuon alpinus Pallas, 1811) Suitable Habitat and Future Climate Refugia Across China

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
The dhole (Cuon alpinus), an endangered carnivore species and one of China's highest‐level protected animals, faces significant threats from both climate change and human disturbance. Since the 1980s, dhole habitat has dramatically shrunk by approximately half, with the current main stronghold being the Qinghai‐Tibet Plateau.
Taifu Huang   +11 more
wiley   +1 more source

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