Results 81 to 90 of about 33,635 (254)

Modulation of CaMKII levels in Wharton’s jelly mesenchymal stem cells under hydrogen peroxide induced stress conditions

Türk Biyokimya Dergisi
Calcium/calmodulin-dependent protein kinase-2 (CaMKII) is a serine/threonine kinase prevalent in neuronal cells, playing a key role in memory, learning, and synaptic plasticity.
San Erkoc Tugba, Gokbayrak Atay Irem Nur, Oztekin Deniz, Gunes Mehmet Emin, Ergur Bekir Ugur, Akan Pinar   +5 more
doaj   +1 more source

Effect of multimeric structure of CaMKII in the GluN2B-mediated modulation of kinetic parameters of ATP. [PDF]

PLoS ONE, 2012
Interaction of GluN2B subunit of N-methyl-D-aspartate receptor with calcium/calmodulin dependent protein kinase II (CaMKII) is critical for the induction of long term potentiation at hippocampal CA3-CA1 synapses.
John Cheriyan, Archana G Mohanan, Pradeep K Kurup, Madhavan Mayadevi, Ramakrishnapillai Vyomakesannair Omkumar   +4 more
doaj   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter and CaMKII in heart [PDF]

Nature, 2014
Arising from M. A. Joiner et al. , 269–273 (2012); doi:10.1038/nature1023410.1038/nature11444 The influx of cytosolic Ca2+ into mitochondria is mediated primarily by the mitochondrial calcium uniporter (MCU)1, a small-conductance, Ca2+-selective channel2,3,4,5,6—MCU modulates intracellular Ca2 ...
Fieni, Francesca, Johnson, Derrick E., Hudmon, Andy, Kirichok, Yuriy   +3 more
openaire   +2 more sources

Mechanism of regulation of Raf-1 by Ca2+/Calmodulin-dependent kinase II [PDF]

, 2011
The calcium-calmodulin dependent kinase II (CaMKII) is an ubiquitous serine/threonine protein kinase involved in multiple signalings and biological functions.
Salzano, Marcella
core  

GST-pull down assay shows that α-I205K-CaMKII and β-K43R-CaMKII can form heteromultimers. [PDF]

, 2012
The mutants, α-I205K-CaMKII and β-K43R-CaMKII, when expressed from a single vector, form heteromultimers and are pulled down by GST-GluN2B. A: Western blot of (α-I205K)-(β-K43R)-CaMKII expressed in insect cell line. The heteromeric CaMKII was prepared by
Archana G. Mohanan (136712), Madhavan Mayadevi (136714), Pradeep K. Kurup (136713), John Cheriyan (136709), Ramakrishnapillai Vyomakesannair Omkumar (136715)   +4 more
core   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source

CaMKII in myocardial hypertrophy and heart failure [PDF]

Journal of Molecular and Cellular Cardiology, 2011
Many signals have risen and fallen in the tide of investigation into mechanisms of myocardial hypertrophy and heart failure (HF). In our opinion, the multifunctional Ca and calmodulin-dependent protein kinase II (CaMKII) has emerged as a molecule to watch, in part because a solid body of accumulated data essentially satisfy Koch's postulates, showing ...
Mark E, Anderson, Joan Heller, Brown, Donald M, Bers   +2 more
openaire   +2 more sources

Slow in Motion but Smart in Learning and Memory: Behavioral Changes in Adult NR3A Knockout Mice [PDF]

, 2011
The expression of NMDA receptor subunit NR3A is high in the neonatal brain but low in adults. However, its functional role in the adult brain is obscure.
Shan Ping Yu, Ling Wei, Osama Mohamad, Mingke Song   +3 more
core   +1 more source

STRUCTURAL STUDIES OF CaMKII ACTIVATION AND OLIGOMERIZATION [PDF]

, 2022
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine kinase that has been shown to carry out various crucial cellular processes.
Özden, Can
core   +1 more source