Results 61 to 70 of about 33,635 (254)

Stellate Ganglionectomy Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction

Frontiers in Bioscience-Landmark
Background: Enhanced cardiac sympathetic activity contributes to chronic heart failure (CHF). Interventions targeting the stellate ganglion (SG) can reduce this activity, potentially slowing the progression of cardiovascular diseases ...
Hui Yan, Xiujun Li, Beilei Liu, Bin Wu, Changgui Chen, Liqun He, Gang Wu   +6 more
doaj   +1 more source

Calcium/Calmodulin-Stimulated Protein Kinase II (CaMKII): Different Functional Outcomes from Activation, Depending on the Cellular Microenvironment

Cells, 2023
Calcium/calmodulin-stimulated protein kinase II (CaMKII) is a family of broad substrate specificity serine (Ser)/threonine (Thr) protein kinases widely expressed in many tissues that is capable of mediating diverse functional responses depending on its ...
John A. P. Rostas, Kathryn A. Skelding
doaj   +1 more source

Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]

, 2010
Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Okuno, Hiroyuki, Redondo, Roger L., Okuno, Hiroyukki, Dr., Spooner, Patrick A., Bito, Haruhiko, Morris, R. G. M. (Richard G. M.), Frenguelli, Bruno G., Morris, Richard G. M.   +7 more
core   +1 more source

PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning

Cell Reports, 2017
Summary: PTEN (phosphatase and tensin homology deleted on chromosome 10) has multiple functions, and recent studies have shown that the PTEN family has isoforms.
Pan Wang, Fan Mei, Jiapan Hu, Minglu Zhu, Hailong Qi, Xi Chen, Ruiqi Li, Michael A. McNutt, Yuxin Yin   +8 more
doaj   +1 more source

Electroacupuncture Attenuates CFA-Induced Inflammatory Pain by Regulating CaMKII

Neural Plasticity, 2020
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine kinase that is ubiquitously distributed in the central and peripheral nervous systems. Moreover, its phosphorylated protein (P-CaMKII) is involved in memory, mood,
Yixiao Gu, Shuangdong Chen, Yunchang Mo, Yingying Tu, Na Chen, Xiaoyong Zhao, Shan Li, Qimin Yu, Qinxue Dai, Junlu Wang   +9 more
doaj   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

CaMKII isoforms. [PDF]

, 2015
A: To evaluate the expression of CaMKII isoforms in ventricular adult cardiomyocytes from WKY rats, the total cell lysates were immunoprecipitated using anti-CaMKII antibody (lane a) or anti-CaMKII α, β γ or δ specific antibodies (lane b) and together to
Daniela Sorriento (447719), Angela Serena Maione (760358), Isabel Gomez-Monterrey (405664), Guido Iaccarino (447721), Marina Sala (760362), Michele Ciccarelli (425329), Maria Rosaria Rusciano (760357), Catherine Crola (760361), Gaetano Santulli (760359), Antonietta Franco (760360), Maddalena Illario (760363), Pietro Campiglia (405663), Carmine Del Giudice (447720), Nicola De Luca (707615), Ersilia Cipolletta (760356), Bruno Trimarco (385299)   +15 more
core   +1 more source

Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36)

Frontiers in Molecular Neuroscience, 2017
AII amacrine cells are essential interneurons of the primary rod pathway and transmit rod-driven signals to ON cone bipolar cells to enable scotopic vision.
Stephan Tetenborg, Shubhash C. Yadav, Sheriar G. Hormuzdi, Hannah Monyer, Ulrike Janssen-Bienhold, Ulrike Janssen-Bienhold, Karin Dedek, Karin Dedek   +7 more
doaj   +1 more source

The Role of CaMKII Overexpression and Oxidation in Atrial Fibrillation—A Simulation Study

Frontiers in Physiology, 2020
This simulation study aims to investigate how the Calcium/calmodulin-dependent protein kinase II (CaMKII) overexpression and oxidation would influence the cardiac electrophysiological behavior and its arrhythmogenic mechanism in atria. A new-built CaMKII
Wei Wang, Wei Wang, Weijian Shen, Shanzhuo Zhang, Gongning Luo, Kuanquan Wang, Yong Xu, Henggui Zhang, Henggui Zhang   +8 more
doaj   +1 more source

CaMKII may regulate renal tubular epithelial cell apoptosis through YAP/NFAT2 in acute kidney injury mice

Renal Failure, 2023
Aim Renal tubular epithelial cell (RTEC) apoptosis is important in acute kidney injury (AKI). Calcium/calmodulin-dependent protein kinase II (CaMKII) plays an important role in cell apoptosis, but its potential role in AKI remains unknown.Methods Using ...
Zongshun Huang, Yonghua Peng, Guibao Ke, Yun Xiao, Yaqi Chen   +4 more
doaj   +1 more source