Results 41 to 50 of about 33,635 (254)
Effects of CaMKII inhibitor tatCN21 on activity-dependent redistribution of CaMKII in hippocampal neurons [PDF]
Neuroscience, 2013 TatCN21 is a membrane permeable calcium/calmodulin-dependent protein kinase II (CaMKII) inhibitor derived from the inhibitor protein CaMKIIN. TatCN21 has been used to demonstrate the involvement of CaMKII in a variety of physiological and pathological phenomena, and it also limits excitotoxic damage in neurons.
J-H, Tao-Cheng +4 more
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The function and role of Ca2+/calmodulin-dependent protein kinase II in lymphocytes [PDF]
, 2021 Ca2+/calmodulin-dependent protein kinase II （CaMKII） はセリン・スレオニンキナーゼの一種でユビキタスに発現している。その機能は脳や心臓でよく知られている一方でそれ以外の細胞におけるCaMKII の機能や役割は発現の広さに反して明らかになっていないことが多い。本稿では免疫細胞のうち，獲得免疫に重要なリンパ球におけるCaMKII の機能をNK 細胞，T 細胞，B 細胞の順にその基本的性質と共に概説する。さらに筆者らが発見したB 細胞のIgE ...
田邊, 香野
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Journal of Inflammation Research, 2022 Xiao-Min Zhang, Ming-Hui Lun, Wei Du, Fang Ma, Ze-Qing Huang Department of Anesthesiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institution, NO.44 Xiaoheyan Road, Dadong District, Shenyang, Liaoning Province, 110042 ...
Zhang XM, Lun MH, Du W, Ma F, Huang ZQ
doaj
Molecular Brain, 2009 Background Previous studies have demonstrated essential roles for alpha-calcium/calmodulin-dependent protein kinase II (alpha-CaMKII) in learning, memory and long-term potentiation (LTP).
Hasegawa Shunsuke +13 more
doaj +1 more source
Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner [PDF]
, 2014 Objective: Enhanced late Na current (late I-Na) induces Na-dependent Ca overload as well as proarrhythmogenic events on the cellular level that include spatio-temporally uncoordinated diastolic Ca release from the sarcoplasmic reticulum (SR) and delayed ...
Shah, Ajay M. +11 more
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The emerging role of CaMKII in cancer
Oncotarget, 2015 Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine kinases best known for its critical role in learning and memory. Recent studies suggested that high levels of CaMKII also expressed in variety of malignant diseases. In this review, we focus on the structure and biology properties of CaMKII, including the role of
Yan-yang, Wang, Ren, Zhao, Hong, Zhe
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NO-dependent CaMKII activation during -adrenergic stimulation of cardiac muscle [PDF]
, 2013 AIMS:During β-adrenergic receptor (β-AR) stimulation, phosphorylation of cardiomyocyte ryanodine receptors by protein kinases may contribute to an increased diastolic Ca(2+) spark frequency. Regardless of prompt activation of protein kinase A during β-AR
Ogrodnik, Jakob +3 more
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UVR Promotes Keratinocyte Phagocytosis and Skin Pigmentation Through TRPA1 Channels
Clinical, Cosmetic and Investigational Dermatology, 2022 Ying Liu,1,* Zhou Li,1,* Wei Wu,1,* Yupeng Wang,1 Guangming Zhao,1 Yuejian Liu,2 Jing Liu,3 Zhiqi Song1 1Department of Dermatology, First Affiliated Hospital of Dalian Medical University, Dalian, People’s Republic of China; 2Central ...
Liu Y +7 more
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CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]
, 2009 The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Borth, Heike +5 more
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Data_Sheet_1_Locally-Induced CaMKII Translocation Requires Nucleotide Binding.PDF [PDF]
, 2020 Calcium-calmodulin-dependent protein kinase (CaMKII) is a molecule involved in several cell processes including plasticity related to learning and memory. Activation of NMDA-type glutamate receptors results in translocation of CaMKII to synapses. However,
Jacqueline K. Rose (8416845) +1 more
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