Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats [PDF]
, 2017 During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells (TRCs)
DeSimone, John A. +12 more
core +3 more sources
Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition
Platelets, 2020 Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia.
Ngan Thi Tran +4 more
doaj +1 more source
Targeting cAMP/PKA pathway for glycemic control and type 2 diabetes therapy.
Journal of Molecular Endocrinology, 2016 In mammals, cyclic adenosine monophosphate (cAMP) is an intracellular second messenger that is usually elicited by binding of hormones and neurotransmitters to G protein-coupled receptors (GPCRs).
Haihua Yang, Linghai Yang
semanticscholar +1 more source
Refugee camp security : decreasing vulnerability through demographic controls [PDF]
, 2011 In the past, refugee camp security has been examined in many lights; however, the demographic make-up of camps has not been focused on. In this article, I present a quantitative model that examines attacks on refugee camps. I argue that the likelihood of
Johnson, Richard
core +1 more source
Cell Death and Disease, 2016 Although cardiac cytosolic cyclic 3′,5′-adenosine monophosphate (cAMP) regulates multiple processes, such as beating, contractility, metabolism and apoptosis, little is known yet on the role of this second messenger within cardiac mitochondria.
Z. Wang +11 more
semanticscholar +1 more source
Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. [PDF]
, 2018 Glaucoma is characterized by a progressive loss of retinal ganglion cells and their axons, but the underlying biological basis for the accompanying neurodegeneration is not known.
Bu, Jung Hyun +8 more
core +2 more sources
Incidence and risk factors of pneumococcal pneumonia in adults: a population-based study
BMC Pulmonary Medicine, 2023 Background Infection caused by Streptococcus pneumoniae, mainly invasive pneumococcal disease (IPD) and pneumococcal pneumonia (PP), are a major public health problem worldwide.
Olga Ochoa-Gondar +8 more
doaj +1 more source
Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]
, 1998 Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F. +1 more
core +1 more source
Cellular and Molecular Life Sciences, 2016 Cyclic adenosine 3, 5′-monophosphate (cAMP) is a ubiquitous second messenger regulating many biological processes, such as cell migration, differentiation, proliferation and apoptosis. cAMP signaling functions not only on the plasma membrane, but also in
Fan Zhang, Liping Zhang, Y. Qi, Hong Xu
semanticscholar +1 more source
Effects of propofol on β-adrenoceptor-mediated signal transduction in cardiac muscle; role of cAMP [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundPropofol may decrease myocardial contractility via actions on the β-adrenoceptor-mediated signal transduction. The aim of this study was to evaluate the effect of propofol via β-adrenoceptor-mediated signal transduction by measuring the tissue ...
Chul Ho Chang, Go Un Roh, Wyun Kon Park
doaj +1 more source