Results 81 to 90 of about 1,724,681 (307)

Myra Breckinridge et le passager clandestin. Kitsch, camp et inconscient hollywoodien

open access: yesRevue LISA, 2017
Strongly criticised for its bad taste upon release, Myra Breckinridge (Michael Sarne, Fox, 1970) was a commercial disaster. It was later rehabilitated as a cult movie thanks to a cultural reevaluation which has considered this narrative experimentation ...
Grégoire Halbout
doaj   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

A (Camp) Flavour of Camp

open access: yesAltre Modernità, 2013
[Fabio Cleto (ed.), Pop ‘camp’, Milano, Marcos y Marcos, 2008, 2 vols., 637 pp. ISBN 978-88-7168-449-9, ISBN 978-88-7168-493-2]
openaire   +4 more sources

Redneck Riviera : kitsch et détournement amusé dans l’imaginaire de John Waters

open access: yesRevue LISA, 2017
Movies by John Waters always feel out of place, neither fully highbrow nor part of the classic underground cinema, they seem to walk a tight rope between avant-garde and exploitation.
Justin S. Wadlow
doaj   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source

Competitive cAMP antagonists for cAMP-receptor proteins.

open access: yesJournal of Biological Chemistry, 1984
The two exocyclic oxygen atoms at phosphorus of cAMP have been replaced by a sulfur atom or by a dimethylamino group. These substitutions introduce chirality at the phosphorus atom; therefore, two diastereoisomers are known for each derivative: (SP)-cAMPS, (RP)-cAMPS, (SP)-cAMPN(CH3)2, and RP-cAMPN(CH3)2.
Haastert, Peter J.M. van   +5 more
openaire   +3 more sources

Cyclic AMP modulation of ion transport across frog retinal pigment epithelium. Measurements in the short-circuit state. [PDF]

open access: yes, 1984
In the frog retinal pigment epithelium (RPE), the cellular levels of cyclic AMP (cAMP) were measured in control conditions and after treatment with substances that are known to inhibit phosphodiesterase (PDE) activity (isobutyl-1-methylxanthine, SQ65442)
Farber, D, Miller, S
core  

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou   +14 more
wiley   +1 more source

Limits To Certainty in QoS Pricing and Bandwidth [PDF]

open access: yes, 2001
Advanced services require more reliable bandwidth than currently provided by the Internet Protocol, even with the reliability enhancements provided by TCP.
Camp, L Jean, Gideon, Carolyn
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

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