The ADCY1-mediated cAMP signaling pathway mediates functional effects of montelukast treatment in brain organoids. [PDF]
Xu Z +9 more
europepmc +1 more source
Lessons from primary school students' perceptions of the factors that influence school connectedness
Abstract School connectedness is critical to improving students' health, development and wellbeing. Research into primary school students' perceptions of the factors that influence their sense of connectedness is essential for identifying practices that promote success.
Jordana F. Hoenig, Therese M. Cumming
wiley +1 more source
Abstract The global teacher shortage continues to intensify, with disparate impacts across geographic and socio‐economic communities. In Queensland, Australia, where this study originates, post‐COVID teacher shortages have intensified workforce pressures, leaving several regional, rural and remote schools as some of the ‘hardest‐to‐staff’ in the ...
Matthew Readette +5 more
wiley +1 more source
Nicotine Impairs Smooth Muscle cAMP Signaling and Vascular Reactivity. [PDF]
Singhrao N +8 more
europepmc +1 more source
IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong +5 more
wiley +1 more source
The AKR1C1-CYP1B1-cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma. [PDF]
Liu C +10 more
europepmc +1 more source
A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates
Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm +3 more
wiley +1 more source
MAGED2 Enhances Expression and Function of NCC at the Cell Surface via cAMP Signaling Under Hypoxia. [PDF]
Radi A +6 more
europepmc +1 more source
KCTD1 regulation of Adenylyl cyclase type 5 adjusts striatal cAMP signaling. [PDF]
Liao Y, Muntean BS.
europepmc +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source

