Results 81 to 90 of about 276,254 (364)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Competitive cAMP antagonists for cAMP-receptor proteins.

Journal of Biological Chemistry, 1984
The two exocyclic oxygen atoms at phosphorus of cAMP have been replaced by a sulfur atom or by a dimethylamino group. These substitutions introduce chirality at the phosphorus atom; therefore, two diastereoisomers are known for each derivative: (SP)-cAMPS, (RP)-cAMPS, (SP)-cAMPN(CH3)2, and RP-cAMPN(CH3)2.
Haastert, Peter J.M. van, Driel, Roel van, Jastorff, Bernd, Baraniak, Janina, Stec, Wojciech J., Wit, René J.W. de   +5 more
openaire   +3 more sources

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Enhancing Outdoor Equipment Marketing through Augmented Reality: A Case Study of Sekaben Camp

Jurnal Sisfokom
Augmented Reality (AR) has the potential to transform product marketing by creating immersive and interactive experiences. This study presents the development of an AR-based application to enhance the marketing of outdoor equipment at Sekaben Camp, a ...
Tri Sugihartono, Rendy Rian Chrisna Putra, Irsad Dwi Sandro   +2 more
doaj   +1 more source

Lisämyynnin parantaminen yritysasiakkaille Top Camping Yyterissä : Haastattelututkimus [PDF]

, 2010
Opinnäytetyön tarkoituksena on tutkia potentiaalisten yritysasiakkaiden halua käyttää Top Camping Yyterin palveluita ja sitä millaisia palveluita yritykset kyseiseltä yritykseltä toivoisivat. Tutkimus tehtiin puhelinhaastatteluna.
Mäkitalo, Noona
core  

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

Ephemeral Domesticity: Campsite Authors

Interiority
The fleeting nature of life and the resulting transformation of inhabited spaces into artefacts that take on different socio-spatial forms through temporary shelters such as cabins, tents, and trailers is a major theme explored particularly in the 1960s ...
Julia Capomaggi
doaj   +1 more source

E.P. Meinecke and the Development of the Modern Auto Campground

IdeAs, 2019
Recreational camping began in the United States in the 1860s after the conclusion of the American Civil War. It was an antimodern response to the rapid industrialization and urbanization that had begun to sweep through America. Americans embraced many of
Terence Young
doaj   +1 more source

Carnarvon Gorge: a comment on the sensitivity of consumer surplus estimation [PDF]

Beal’s (1995) method of estimating the value of Carnarvon Gorge for recreational use is re‐examined. When an inconsistency in her estimation procedure is corrected, the estimated value of Carnarvon Gorge for camping is found to be six times higher.
Chotikapanich, Duangkamon, Griffiths, William E.   +1 more
core   +1 more source

Propuesta de campamentación turística para estudiantes: hacienda y estancia San Isidro, Parroquia Tarqui, Cantón Cuenca [PDF]

, 2015
El desarrollo de la presente monografía, tiene como objetivo principal crear una propuesta de campamentación turística para la Hacienda y Estancia San Isidro, debido a que en la actualidad en la ciudad de Cuenca no existe un establecimiento dirigido al ...
Núñez Vázquez, Paola Cristina, Vinces García, Oscar Enmanuel   +1 more
core