Results 211 to 220 of about 233,434 (291)

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

open access: yesAngewandte Chemie, EarlyView.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar   +8 more
wiley   +2 more sources

Vahan Samvedak: a comprehensive real-time college bus tracking and safety system. [PDF]

open access: yesSci Rep
Chauhan Y   +8 more
europepmc   +1 more source

Gephyrin Neurological Autoimmunity

open access: yesAnnals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano   +10 more
wiley   +1 more source

Isolation of a Highly Reactive CBNC Heterocumulene via Azidoborylene Photolysis: Facile Access to a Crystalline Dioxaborirane

open access: yesAngewandte Chemie, EarlyView.
Azidoborylene photolysis results in the isolation of a reactive C═B═N═C heterocumulene bearing an ambiphilic boron centre. Addition of 3O2 to this species results in the clean conversion to a unique example of a dioxaborirane. ABSTRACT Oxidation of the formal boron(0) complex MeCAAC2B in the presence of tetrabutylammonium azide leads to the formation ...
Hayley King   +4 more
wiley   +2 more sources

Analysis of Maintenance Activities on Campus Information System

open access: yesAbstracts of Annual Conference of Japan Society for Management Information, 2012
Wada, Hatsue, Yoshida, Taketoshi
openaire   +1 more source

Increasing TET Expression and 5‐Hydroxymethylcytosine Formation by a Carbocyclic 5‐Aza‐2′‐deoxy‐cytidine Antimetabolite

open access: yesAngewandte Chemie, EarlyView.
The carbocyclic Decitabine analog (cAzadC) incorporates as an antimetabolite weakly into the genome of growing tumor cells, where it triggers a genome‐wide demethylation and a surprisingly strong hydroxymethylation of cytosine, which translates into an efficient in vivo antitumor (AML) effect.
Maike Däther   +17 more
wiley   +2 more sources

Post‐Translational Isoaspartate Promotes Amyloid Formation in β2‐Microglobulin

open access: yesAngewandte Chemie, EarlyView.
Chemical synthesis of five β2‐microglobulin (β2m) variants reveals the structural impact of Asn deamidation. By introducing Asp or isoAsp at susceptible Asn‐Gly sequences, we demonstrate that isoAsp17 formation specifically accelerates amyloid fibril formation, highlighting its potential contribution to dialysis‐related amyloidosis.
Ryuji Kawakami   +5 more
wiley   +2 more sources

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