Results 31 to 40 of about 609,916 (309)

Reply to Frański, R.; Beszterda-Buszczak, M. Comment on “Villalva et al. Antioxidant, Anti-Inflammatory, and Antibacterial Properties of an Achillea millefolium L. Extract and Its Fractions Obtained by Supercritical Anti-Solvent Fractionation against Helicobacter pylori. Antioxidants 2022, 11, 1849”

Antioxidants, 2023
Franski and Beszterda-Buszczak [...]
Marisol Villalva, Jose Manuel Silvan, Teresa Alarcón-Cavero, David Villanueva-Bermejo, Laura Jaime, Susana Santoyo, Adolfo J. Martinez-Rodriguez   +6 more
doaj   +1 more source

Juan Latino "El Negro": Poet and Humanist [PDF]

, 2015
The article explores the historical novel written by José V. Pascual about the life and Works of Juan Latino "El Negro" focusing on the humanism of this black poet and professor and his contributions to the Afro-spanish historical memory.Universidad de ...
Castro-Borrego, Silvia Pilar
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Antioxidant, Anti-Inflammatory, and Antibacterial Properties of an Achillea millefolium L. Extract and Its Fractions Obtained by Supercritical Anti-Solvent Fractionation against Helicobacter pylori

Antioxidants, 2022
The main objective of this work is to evaluate the potential utility of an Achillea millefolium extract (yarrow extract, YE) in the control of H. pylori infection.
Marisol Villalva, Jose Manuel Silvan, Teresa Alarcón-Cavero, David Villanueva-Bermejo, Laura Jaime, Susana Santoyo, Adolfo J. Martinez-Rodriguez   +6 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Procyanidin-Rich Extract from Grape Seeds as a Putative Tool against Helicobacter pylori

Foods, 2020
Strains of Helicobacter pylori (H. pylori) resistant to various antibiotics have increased in recent years. In this context, the search for new therapeutic approaches is crucial.
Jose Manuel Silvan, Alba Gutiérrez-Docio, Silvia Moreno-Fernandez, Teresa Alarcón-Cavero, Marin Prodanov, Adolfo J. Martinez-Rodriguez   +5 more
doaj   +1 more source

Pressurized Liquid Extraction for the Production of Extracts with Antioxidant Activity from Borututu (Cochlospermum angolense Welw.)

Foods, 2023
Borututu (Cochlospermum angolense Welw.) roots have been described as a rich source of phenolic compounds. Despite the potential of this plant for the production of bioactive extracts, studies reported until now have been scarce, and they have been based
Honória S. Chipaca-Domingos, Federico Ferreres, Tiziana Fornari, Angel Gil-Izquierdo, Benevides C. Pessela, David Villanueva-Bermejo   +5 more
doaj   +1 more source

Tracking advanced persistent threats in critical infrastructures through opinion dynamics [PDF]

, 2018
Advanced persistent threats pose a serious issue for modern industrial environments, due to their targeted and complex attack vectors that are difficult to detect.
A Lemay, C-T Lin, DJ Watts, EM Hutchins, GA Pagani, J Kneis, JE Rubio, L Cazorla, P Chen, R Hegselmann, TW Haynes   +10 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

“New Critical Approaches to the History of the Early English Novel” [PDF]

, 2017
The critical appraisal of the rise of the novel in English has changed drastically from the publication of Ian Watt’s homonymous study in 1957. Some thirty years later, one of Watt’s disciples, Michael McKeon, suggested a new model to study the origins ...
Villegas López, Sonia
core