Results 51 to 60 of about 57,117 (221)

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

In Vitro Study of Immune Properties of New Lactobacilli Isolates from Pheasant Gut

open access: yesFolia Veterinaria, 2020
The goal of this paper was to study the effect of Lactobacillus reuteri B1/1, B2/1 and B6/1 on the relative expression of selected interleukins (IL-1β, IL-15), macrophage inflammatory protein (MIP-1β), and the relative percentage of T lymphocyte ...
Karaffová V.   +5 more
doaj   +1 more source

Campylobacter [PDF]

open access: yesVeterinary Research, 2005
Species within the genus, Campylobacter, have emerged over the last three decades as significant clinical pathogens, particularly of human public health concern, where the majority of acute bacterial enteritis in the Western world is due to these organisms. Of particular concern are the species, C. jejuni and C.
John E, Moore   +15 more
openaire   +2 more sources

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

open access: yesInterdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang   +14 more
wiley   +1 more source

Sequelae of Foodborne Illness Caused by 5 Pathogens, Australia, Circa 2010

open access: yesEmerging Infectious Diseases, 2014
In Australia circa 2010, 4.1 million (90% credible interval [CrI] 2.3–6.4 million) episodes of foodborne gastroenteritis occurred, many of which might have resulted in sequelae.
Laura Ford   +3 more
doaj   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow   +4 more
wiley   +1 more source

Genome maps of Campylobacter jejuni and Campylobacter coli [PDF]

open access: yesJournal of Bacteriology, 1992
Little information concerning the genome of either Campylobacter jejuni or Campylobacter coli is available. Therefore, we constructed genomic maps of C. jejuni UA580 and C. coli UA417 by using pulsed-field gel electrophoresis. The genome sizes of C. jejuni and C. coli strains are approximately 1.7 Mb, as determined by SalI and SmaI digestion (N.
D E, Taylor, M, Eaton, W, Yan, N, Chang
openaire   +2 more sources

Mapping the subgingival HerBiome and HisBiome over the human healthspan

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam   +3 more
wiley   +1 more source

Campylobacter species in chilean patients with chronic periodontitis

open access: yesBioscience Journal, 2018
The purpose of this study is to identify the presence of species of genus  The purpose of this study is to identify the presence of Campylobacter species (C. rectus, C. concisus, C. gracilis and C.
Hans Montanares   +5 more
doaj   +1 more source

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