Results 41 to 50 of about 5,102,780 (337)

Functional Inequalities: New Perspectives and New Applications [PDF]

open access: yes, 2012
This book is not meant to be another compendium of select inequalities, nor does it claim to contain the latest or the slickest ways of proving them.
Amir Moradifam   +2 more
core  

Time variation in the dynamics of worker flows:evidence from North America and Europe [PDF]

open access: yes, 2014
Vector autoregressive methods have been used to model the interrelationships between job vacancy rates, job separation rates and job-finding rates using tools such as impulse response analysis.
Blanchard   +28 more
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2 [PDF]

open access: yes, 2017
We thank Zhen-Yuan Lin for help in the preparation of the AP-MS samples, and Cathy Collins for technical assistance. MDL is supported by a Sir Henry Wellcome Postdoctoral Fellowship (Wellcome Trust 096072), LEC is supported by a Canada Research Chair in ...
Bohovych, Iryna   +7 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

La Comercialización Internacional del Turismo Comunitario. La Experiencia en América Latina

open access: yesARA: Revista de Investigación en Turismo, 2017
En el debate sobre la viabilidad del turismo comunitario se ha reconocido que la comercialización es un factor clave para sus posibilidades de éxito.
Ernest Cañada
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Why are young Canadian men avoiding the humanities? [PDF]

open access: yesThe Young Researcher, 2023
Historically, the humanities have been highly respected. Since the mid-20th century, however, these fields of study have experienced an immense decline in undergraduate enrollment.
Arjun Deckha
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

La participación de las personas trans en la actividad física y el deporte: barreras y facilitadores

open access: yesArxius de Ciències Socials
Las personas trans son uno de los colectivos más vulnerados en nuestra sociedad. A pesar de los beneficios fisiológicos y psicosociales que puede reportar la práctica de actividad física y deporte (AFD), las personas trans presentan niveles de práctica ...
Elena López-Cañada
doaj   +1 more source

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