Results 61 to 70 of about 4,735,522 (306)
FACETS, 2021 Both the Truth and Reconciliation Commission (TRC) and the National Inquiry into Missing and Murdered Indigenous Women and Girls (MMIWG) explicitly emphasized the role of educators in “reconciliation.” Alongside this, conservation practitioners are ...
Danika Billie Littlechild +2 more
doaj +1 more source
, 1992 This forward, written ten years after the adoption of the Constitution of Canada, draws sharp comparisons between Canada’s constitution and the United States’ original governing document, the Articles of ...
Van Alstyne, William W.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The formation of Laurentia : Evidence from shear wave splitting [PDF]
, 2017 The authors would like to thank A. Walker for invaluable help understanding the MSAT forward modelling code, as well as A. Boyce, L. Petrescu, and C.
Bastow, Ian +4 more
core +2 more sources
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Issue 16: Irregular Migration to Canada: Addressing Current Policy Responses that Impact Refugee Claimants’ Arrival and Settlement in the Country [PDF]
, 2019 The unexpected influx of refugee claimants irregularly crossing the US-Canada border since 2016 has strained Canada’s immigration system. According to the Immigration and Refugee Board of Canada (IRB), 47,425 claims were referred to the IRB in 2017, and ...
Romero, Monica
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Education Policy Analysis Archives, 2020 State-mandated curriculum policy documents have an important political function. Governments use them to make ideological statements about the role of schools and how the next generation of citizens are to be shaped. Beginning from this premise, we use a
Jesse K. Butler, Peter Milley
doaj +1 more source
Why ban sex hormones in the nursery? [PDF]
, 2008 Canada leads the world with new regulations to prohibit the importation, sale and advertising of polycarbonate baby bottles that contain bisphenol A (BPA).
Paull, John
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source