Results 41 to 50 of about 4,735,522 (306)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Public servant schools in Canada: A concept for reconciliation [PDF]
, 2017 The Truth and Reconciliation Commission of Canada has called on federal, provincial, territorial, and municipal governments of Canada to educate public servants about the history and legacy of Indian residential schools and related topics, such as the ...
Weiler, Mark
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
La Comercialización Internacional del Turismo Comunitario. La Experiencia en América Latina
ARA: Revista de Investigación en Turismo, 2017 En el debate sobre la viabilidad del turismo comunitario se ha reconocido que la comercialización es un factor clave para sus posibilidades de éxito.
Ernest Cañada
doaj
ICROFS news 2/2012. Newsletter from ICROFS [PDF]
, 2012 International organic research theme: - Organic farming in Canada - Linking organic knowledge - Organic greenhouse production research in Canada - Researhing a limiting and limited nutrient - Prodctivity and growth in organic value chains (ProGrOV)
Mathiesen, C., Sørensen, L.S.
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
La participación de las personas trans en la actividad física y el deporte: barreras y facilitadores
Arxius de Ciències SocialsLas personas trans son uno de los colectivos más vulnerados en nuestra sociedad. A pesar de los beneficios fisiológicos y psicosociales que puede reportar la práctica de actividad física y deporte (AFD), las personas trans presentan niveles de práctica ...
Elena López-Cañada
doaj +1 more source
Journal of Comparative Effectiveness Research, 2023 Aim: Clinical trials and real-world data for Type 2 diabetes have shown that real-time continuous glucose monitoring (rt-CGM) lowers glycated hemoglobin (A1c) and reduces hypoglycemia relative to self-monitoring of blood glucose (SMBG).
Hamza Alshannaq +6 more
doaj +1 more source
Longing for evidence-based traditions
Medicine Anthropology Theory, 2020 In Native North America, clinical/healing spaces are caught up in political struggles for autonomy. In Canada’s Northwest Territories, where rates of alcohol consumption are substantially higher than national averages, there are ongoing attempts to align
Lindsay Bell
doaj +1 more source