Results 51 to 60 of about 4,735,522 (306)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Canada's call [PDF]

Science, 2018
Next month, Canada will host the Group of 7 (G7) summit in picturesque Charlevoix, Québec. As leaders from Canada, France, Germany, Italy, Japan, the United Kingdom, and the United States come together, along with European Union representatives, to discuss the progressive agenda, science will be on everyone's mind. With science and technology playing a
openaire   +2 more sources

Functional Inequalities: New Perspectives and New Applications [PDF]

, 2012
This book is not meant to be another compendium of select inequalities, nor does it claim to contain the latest or the slickest ways of proving them.
Amir Moradifam, Council Of Canada, Nassif Ghoussoub   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Un estudio exploratorio de las experiencias de las personas trans en educación física

Arxius de Ciències Socials
La literatura coincide en señalar que la asignatura de Educación física (EF) refleja y remarca las desigualdades existentes en la sociedad. Para las personas trans, la EF puede resultar especialmente difícil debido a los discursos binarios del género ...
Elena López-Cañada
doaj   +1 more source

Financial knowledge, financial confidence and learning capacity on financial behavior: a Canadian study

Cogent Social Sciences, 2022
This study examines the relationships between financial knowledge, confidence, learning capacity, education and other sociodemographic information and financial behavior.
Tania Morris, Stephanie Maillet, Vivi Koffi   +2 more
doaj   +1 more source

Reconsidering: The Church\u27s Constitution [PDF]

, 1995
Evangelical Lutheran Church in ...
Hordern, William Edward
core   +1 more source

Review of Czech Refugees in Cold War Canada by Jan Raska [PDF]

, 2020
Review of Czech Refugees in Cold War Canada by Jan ...
Falconer, Thirstan
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

¿"Libre expresión gráfica" en dictadura? Las Jornadas del Color y de la Forma

Question, 2015
En plena dictadura militar, en Buenos Aires, Mirtha Dermisache y el Taller de Acciones Creativas por ella coordinado organizó una serie de experiencias conocidas como Jornadas del Color y de la Forma.
Lucía Cañada
doaj