Results 41 to 50 of about 34,375 (153)

Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series

The Pan African Medical Journal, 2018
Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue.
Montassar Ghalleb, Hatem Bouzaiene, Sarah Sghaier, Hanen Bouaziz, Monia Hechiche, Jamel Ben Hassouna, Khaled Rahal   +6 more
doaj   +1 more source

In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptors' Down-regulation and Dimers' Disruption

Neoplasia: An International Journal for Oncology Research, 2012
We previously demonstrated the synergistic therapeutic effect of the cetuximab (anti-epidermal growth factor receptor [EGFR] monoclonal antibody, mAb)-trastuzumab (anti-HER2 mAb) combination (2mAbs therapy) in HER2low human pancreatic carcinoma ...
Christel Larbouret, Nadège Gaborit, Thierry Chardès, Mickaël Coelho, Emmanuelle Campigna, Caroline Bascoul-Mollevi, Jean-Pierre Mach, David Azria, Bruno Robert, André Pèlegrin   +9 more
doaj   +1 more source

Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance

Nature Communications, 2022
Different mechanisms have been reported to explain resistance to chemotherapy in cancer. Here, the authors show that the chemotherapeutic drug 5-fluorouracil alters the function of ribosomes to promote pro-survival gene translation leading to ...
Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C. Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz   +31 more
doaj   +1 more source

A RiboCancer cell line panel reveals that CLL‐associated Rps15 mutations translationally rewire transcription through codon‐specific tRNA accommodation defects

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Recurrent point mutations in ribosomal proteins (RPs) RPL10 and RPS15 are found in T‐cell acute lymphoblastic leukemia (T‐ALL) and chronic lymphocytic leukemia (CLL), respectively. Furthermore, deletions of RPL5, RPL11, and RPL22 are frequent in hematologic diseases such as Diamond Blackfan Anemia, T‐ALL, multiple myeloma, and in a variety of ...
Anaïs Astier, Marino Caruso, Stijn Vereecke, Paulo E. Santo, Coralie Capron, Carine Froment, Dana Rinaldi, David Cabrerizo Granados, Marine Leclercq, Jonathan Royaert, Jelle Verbeeck, Naomy Pasau, Laura Plassart, Daniele Pepe, Steven Verbruggen, Hermes Paraqindes, Simon Lebaron, Virginie Marcel, Sébastien Durand, Clément Chapat, Gerben Menschaert, Pierre Close, Francesca Rapino, Frédéric Catez, Julien Marcoux, Célia Plisson‐Chastang, Kim De Keersmaecker   +26 more
wiley   +1 more source

Elaboration et intérêt d'une base de données en consultation de cancérologie [PDF]

, 2003
L'objectif de ce travail était d'élaborer une base de données en cancérologie vétérinaire afin de valoriser la consultation de cancérologie à l'Ecole Nationale Vétérinaire de Toulouse.
Mossiere, Laurent
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Tests diagnostiques et thérapies ciblées en cancérologie

, 2012
Les avancées récentes de la biologie moléculaire ont conduit à la mise à disposition de nouvelles molécules très coûteuses en cancérologie : les thérapies moléculaires ciblées.
Valérie Seror, Anthony Gonçalves, Marino, Patricia, Gonçalves, Anthony, Bertucci, François, François Bertucci, Seror, Valérie, Patricia Marino   +7 more
core   +1 more source

Progression-Free Survival Under Immune Checkpoint Inhibitors for Metastatic Non-Small-Cell Lung Cancer: A Retrospective Cohort Study

Oncology and Therapy
Introduction Immune checkpoint inhibitors (ICI) are the standard of care for non-small-cell lung cancer (NSCLC) regardless of program death ligand-1 (PDL1) expression.
Paul Boré, Margaux Geier, Loïc Campion, Jean-Luc Raoul, Ludovic Doucet, Sandrine Hiret, Frédéric Bigot, François Bocquet, Laura Mezquita, Teresa Gorria, Judith Raimbourg   +10 more
doaj   +1 more source

The theranostic: an innovative combination for the diagnosis and therapy of cancers

Journal de la Faculté de Médecine d'Oran, 2022
La recherche en cancérologie doit répondre à un double défi : le diagnostic précoce des tumeurs pour permettre une thérapie efficace et le développement de nouvelles thérapies ciblées. Dans la lutte contre le cancer, les recherches actuelles s’orientent
Nassima MOUSSAOUI
doaj  

Anatomy-based correction of kidney PVE on $$^{177}\text{Lu}$$ 177 Lu SPECT images

EJNMMI Physics
Background In peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images paves the way for patient-specific treatment.
Julien Salvadori, Oreste Allegrini, Thomas Opsommer, Josefina Carullo, David Sarrut, Clemence Porot, Florian Ritzenthaler, Philippe Meyer, Izzie-Jacques Namer   +8 more
doaj   +1 more source

Les marqueurs de prolifération en oncologie vétérinaire : applications à l'étude pronostique du mastocytome cutané canin [PDF]

, 2001
Le mastocytome cutané représente un type tumoral dominant de la cancérologie du chien mais demeure l'une des tumeurs canines au comportement clinique les plus imprévisibles.
Abadie, Jérôme
core