Results 31 to 40 of about 10,542 (115)
EJNMMI PhysicsBackground Intravenous administration of $$^{177}$$ Lu-labeled radiopharmaceuticals (RPMs) such as PSMA and DOTATATE entails a risk of extravasation, potentially resulting in absorbed doses exceeding thresholds for deterministic tissue damage.
Olivia Lienhardt +7 more
doaj +1 more source
Small, EarlyView.We developed core‐shell iron oxide@ZIF‐8 magnetic‐MOF nanohybrids via a seeded growth method for magnetic hyperthermia‐triggered drug delivery. Cubic cores and thinner shells maximized heating. In‐situ doxorubicin encapsulation achieved 98% loading, better than surface encapsulation. Polymer coating improved stability.
Ana Maria Panaite +11 more
wiley +1 more source
HIV Medicine, EarlyView.Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart +10 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, Volume 20, Issue 8, Page 1905-1912, August 2026.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.Abstract Background Accurate dose deposition in superficial radiotherapy remains challenging due to the inherent skin‐sparing effect of megavoltage photon beams and difficulties in ensuring bolus conformity. Purpose This study aims to comprehensively evaluate the dosimetric characteristics of the room‐temperature‐malleable high‐density bolus, to ...
Jonathan Dadoun +15 more
wiley +1 more source
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.A series of 25 functionalized indeno[1,2‐b]indoles was selected from in‐house compound library and additional synthesis work. Capillary electrophoresis‐based and thermal shift assays, X‐ray analysis of small molecules, and co‐crystallization studies highlighted a key molecular template for the inhibitory potential of protein kinase CK2.
Matheus M. Guimarães +18 more
wiley +1 more source
Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
The Pan African Medical Journal, 2018 Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue.
Montassar Ghalleb +6 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2012 We previously demonstrated the synergistic therapeutic effect of the cetuximab (anti-epidermal growth factor receptor [EGFR] monoclonal antibody, mAb)-trastuzumab (anti-HER2 mAb) combination (2mAbs therapy) in HER2low human pancreatic carcinoma ...
Christel Larbouret +9 more
doaj +1 more source
Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance
Nature Communications, 2022 Different mechanisms have been reported to explain resistance to chemotherapy in cancer. Here, the authors show that the chemotherapeutic drug 5-fluorouracil alters the function of ribosomes to promote pro-survival gene translation leading to ...
Gabriel Therizols +31 more
doaj +1 more source
Chondroid Soft Tissue Tumors With FOS::PABPN1 Fusion: A New Entity? About Two Cases
Genes, Chromosomes and Cancer, Volume 65, Issue 8, August 2026.ABSTRACT Soft tissue tumors with chondroid matrix represent a heterogeneous group with persistent diagnostic challenges. Advances in molecular diagnostics have identified recurrent gene fusions in several chondroid neoplasms, predominantly involving FN1. Here, we report two cases of chondroid tumors harboring a novel FOS::PABPN1 fusion.
Jinane Kharmoum +7 more
wiley +1 more source