Results 31 to 40 of about 10,799 (115)
Purpose Brain metastases (BMs) are the leading cause of intracranial malignant neoplasms in adults. WHO, Karnofsky performance status (KPS), age, number of BMs, extracerebral progression (ECP), recursive partitioning analysis (RPA), diagnosis-specific ...
L. Kuntz +8 more
doaj +1 more source
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine and epithelial skin cancer. Somatostatin analogues, such as lanreotide, have shown efficacy in managing other neuroendocrine tumors. Retrospective studies suggest that lanreotide may induce partial response or disease stabilization in patients with advanced MCC.
Julie Charles +23 more
wiley +1 more source
We developed core‐shell iron oxide@ZIF‐8 magnetic‐MOF nanohybrids via a seeded growth method for magnetic hyperthermia‐triggered drug delivery. Cubic cores and thinner shells maximized heating. In‐situ doxorubicin encapsulation achieved 98% loading, better than surface encapsulation. Polymer coating improved stability.
Ana Maria Panaite +11 more
wiley +1 more source
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart +10 more
wiley +1 more source
We previously demonstrated the synergistic therapeutic effect of the cetuximab (anti-epidermal growth factor receptor [EGFR] monoclonal antibody, mAb)-trastuzumab (anti-HER2 mAb) combination (2mAbs therapy) in HER2low human pancreatic carcinoma ...
Christel Larbouret +9 more
doaj +1 more source
Abstract Liver transplantation (LT) may offer survival or symptomatic benefit for highly selected patients with advanced, well‐differentiated small‐intestinal or pancreatic neuroendocrine tumours and unresectable liver‐dominant metastases. However, its role remains controversial, as LT is rarely curative, recurrence is common, and benefits must be ...
Peter Stålberg +11 more
wiley +1 more source
Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue.
Montassar Ghalleb +6 more
doaj +1 more source
Two new cases of low‐grade diffusely infiltrative tumour (LGDIT), SMARCB1 mutant, are described in an 18‐year‐old and a 50‐year‐old male, both with supratentorial lesions, characteristic rhabdoid histology on a myxoid‐collagenous background, and complete INI1 loss.
Alice Métais +13 more
wiley +1 more source
Humans encounter a wide range of natural and synthetic chemicals throughout their lifespan and these exposures have a complex impact on health outcomes.
Marie Robert +6 more
doaj +1 more source
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud +12 more
wiley +1 more source

