Results 11 to 20 of about 10,799 (115)

Innovative Dose-Response Assessment of the Metaboreflex With Indirect Control of Intramuscular Metabolic Perturbation in Humans. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim We aimed to evaluate an innovative dose–response approach to assess the metaboreflex with control of intramuscular metabolic perturbation (concept of metaboreflex gain). We also investigated potential sex differences in the metaboreflex using this new approach.
Kouzkouz N, Mallard J, Hucteau E, Schott R, Pivot X, Ducrocq GP, Hureau TJ.   +6 more
europepmc   +2 more sources

Influence of pneumatic transportation on the stability of monoclonal antibodies

Scientific Reports, 2023
Pneumatic transportation systems (PTS) were recently proposed as a method to carry ready-for-injection diluted monoclonal antibodies (mAbs) from the pharmacy to the bedside of patients.
Pierre Coliat, Stéphane Erb, Hélène Diemer, Dan Karouby, Tristan Martin, Mainak Banerjee, Chen Zhu, Martin Demarchi, Sarah Cianférani, Alexandre Detappe, Xavier Pivot   +10 more
doaj   +1 more source

Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report

Journal of Medical Case Reports, 2023
Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell ...
Alexandra-Ioana Pușcașu, Fabien Moinard-Butot, Delphine Antoni, Roland Schott, Laura Somme   +4 more
doaj   +1 more source

Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

Biomarker Research, 2020
Background Ibrutinib, an irreversible Bruton Tyrosine Kinase (BTK) inhibitor, has revolutionized Chronic Lymphocytic Leukemia (CLL) treatment, but resistances to ibrutinib have emerged, whether related or not to BTK mutations.
Sarah Cadot, Carine Valle, Marie Tosolini, Frederic Pont, Laetitia Largeaud, Camille Laurent, Jean Jacques Fournie, Loic Ysebaert, Anne Quillet-Mary   +8 more
doaj   +1 more source

Adjuvant radiation therapy for malignant Abrikossoff’s tumor: a case report about a femoral triangle localisation

Radiation Oncology, 2018
Background Granular cell or Abrikossoff’s tumors are usually benign however rare malignant forms concern 1 to 3% of cases reported. Pelvic locations are exceptional.
C. Marchand Crety, C. Garbar, G. Madelis, F. Guillemin, P. Soibinet Oudot, J. C. Eymard, S. Servagi Vernat   +6 more
doaj   +1 more source

Acute toxicities and cumulative dose to the brain of repeated sessions of stereotactic radiotherapy (SRT) for brain metastases: a retrospective study of 184 patients

Radiation Oncology, 2023
Background Stereotactic radiation therapy (SRT) is a focal treatment for brain metastases (BMs); thus, 20 to 40% of patients will require salvage treatment after an initial SRT session, either because of local or distant failure.
L. Kuntz, C. Le Fèvre, D. Jarnet, A. Keller, P. Meyer, A. Thiery, H. Cebula, G. Noel, D. Antoni   +8 more
doaj   +1 more source

Validation of a high performance functional assay for individual radiosensitivity in pediatric oncology: a prospective cohort study (ARPEGE)

BMC Cancer, 2018
Background Approximately 900 children/adolescents are treated with radiotherapy (RT) every year in France. However, among the 80% of survivors, the cumulative incidence of long-term morbidity – including second malignancies - reach 73.4% thirty years ...
Valérie Bernier-chastagner, Liza Hettal, Véronique Gillon, Laurinda Fernandes, Cécile Huin-schohn, Marion Vazel, Priscillia Tosti, Julia Salleron, Aurélie François, Elise Cérimèle, Sandrine Perreira, Didier Peiffert, Pascal Chastagner, Guillaume Vogin   +13 more
doaj   +1 more source

La guérison en cancérologie : une improbable ambition

Saúde e Sociedade
Résumé Cet article propose une réflexion sur la notion de guérison et sur ses usages en cancérologie. Un premier point ausculte sa mise en œuvre en tant qu’ambition à la fois médicale et politique suprême de la mission fondatrice de la cancérologie ...
Marie Ménoret
doaj   +1 more source

Standard 6-week chemoradiation for elderly patients with newly diagnosed glioblastoma

Scientific Reports, 2021
Glioblastoma (GBM) is frequent in elderly patients, but their frailty provokes debate regarding optimal treatment in general, and the standard 6-week chemoradiation (CRT) in particular, although this is the mainstay for younger patients.
Loïg Vaugier, Loïc Ah-Thiane, Maud Aumont, Emmanuel Jouglar, Mario Campone, Camille Colliard, Ludovic Doucet, Jean-Sébastien Frenel, Carole Gourmelon, Marie Robert, Stéphane-André Martin, Tanguy Riem, Vincent Roualdes, Loïc Campion, Augustin Mervoyer   +14 more
doaj   +1 more source

Phénotypage de la Dihydropyrimidine Déshydrogénase et Tolérance aux Chimiothérapies à Base de Fluoropyrimidine : Une Étude de Cohorte Rétrospective au Gabon

Health Research in Africa
RÉSUMÉ Introduction. Les fluoropyrimidines, pierre angulaire de nombreuses chimiothérapies, peuvent induire des toxicités sévères et potentiellement létales chez les patients présentant un déficit en dihydropyrimidine déshydrogénase (DPD).
Nzamba BPL, Nziengui Tirogo C, Okourimakima Nguia M, Filankembo A, Edzang KN, Igabouyi C, Belembaogo E   +6 more
doaj   +1 more source