Results 1 to 10 of about 10,780 (98)

SPINAL: study protocol for a multicenter non-inferiority trial evaluating reduce vertebral irradiation volumes in palliative radiotherapy for spinal bone metastases on analgesic efficacy [PDF]

BMC Cancer
Background Palliative analgesic radiotherapy is commonly used to alleviate pain in patients with bone metastases. Traditionally, this approach involved irradiating the vertebrae above and below the painful lesion.
Jean-Christophe Faivre, Aurélien Lambert, Marie Bruand, Adrian Francais, Stéphane Supiot, Sébastien Thureau, Vincent Bourbonne, Florine Tomaszewski, Claire Charra-Brunaud, Jean-François Py, Anaïs Stefani, Maria Jolnerovski, Nicolas Demogeot, Mathilde Cuenin, Sophie Renard, Selima Sellami, Ida Trampetti, Valérie Bernier-Chastagner, Juliette Jacques, Emma Agnoux, Richard Au Appavou, William Gehin, Nicolas Martz, Nour Mammari   +23 more
doaj   +2 more sources

Operationalizing the EU AI Act in a comprehensive cancer center through an institutional governance framework [PDF]

npj Digital Medicine
The EU AI Act subjects high-risk clinical AI systems to deployer obligations whose institutional operationalization remains undefined. Drawing on experience at a French comprehensive cancer center, we present a governance framework combining three novel ...
W. Gehin, JC Faivre, JE Bibault, Y. Thiery, S. Deon, E. Desandes, A. Lambert, A. Baudin, M. Schoumacker, P. Eschwege, S. Supiot, T. Perennec, D. Peiffert   +12 more
doaj   +2 more sources

Bricolage médical. Savoirs et pratiques des oncologues cambodgiens

Moussons, 2021
This article analyzes the ways in which oncologists practice medicine in Cambodia. It focuses on everyday practices and describes the processes of biomedical adaptation and appropriation, in other words, to describe how physicians adapt their knowledge ...
Meriem M’zoughi
doaj   +1 more source

La collégialité dans la mise en place d’une sédation profonde et continue dans un centre de cancérologie en France

Canadian Journal of Bioethics, 2023
Une procédure collégiale désigne le fait de recueillir, avant de prendre une décision médicale délicate, l’avis de l’ensemble de l’équipe de soins responsable du patient, incluant le personnel infirmier et aide-soignant, entre autres.
Bettina Couderc, Alfonsina Faya Robles, Nathalie Caunes-Hilary, Laurie Galiby, Emmanuelle Rial Sebbag   +4 more
doaj   +1 more source

Comparison of four synthetic CT generators for brain and prostate MR-only workflow in radiotherapy

Radiation Oncology, 2023
Background The interest in MR-only workflows is growing with the introduction of artificial intelligence in the synthetic CT generators converting MR images into CT images.
Damien Autret, Camille Guillerminet, Alban Roussel, Erwan Cossec-Kerloc’h, Stéphane Dufreneix   +4 more
doaj   +1 more source

Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers

OncoImmunology, 2021
γδ T lymphocytes diverge from conventional T CD8 lymphocytes for ontogeny, homing, and antigen specificity, but whether their differentiation in tumors also deviates was unknown.
Juan-Pablo Cerapio, Marion Perrier, Camille-Charlotte Balança, Pauline Gravelle, Fréderic Pont, Christel Devaud, Don-Marc Franchini, Virginie Féliu, Marie Tosolini, Carine Valle, Fréderic Lopez, Anne Quillet-Mary, Loic Ysebaert, Alejandra Martinez, Jean Pierre Delord, Maha Ayyoub, Camille Laurent, Jean-Jacques Fournie   +17 more
doaj   +1 more source

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

Scientific Reports, 2021
In ovarian carcinoma, anti-Müllerian hormone (AMH) type II receptor (AMHRII) and the AMH/AMHRII signaling pathway are potential therapeutic targets. Here, AMH dose-dependent effect on signaling and proliferation was analyzed in four ovarian cancer cell ...
Maëva Chauvin, Véronique Garambois, Pierre-Emmanuel Colombo, Myriam Chentouf, Laurent Gros, Jean-Paul Brouillet, Bruno Robert, Marta Jarlier, Karen Dumas, Pierre Martineau, Isabelle Navarro-Teulon, David Pépin, Thierry Chardès, André Pèlegrin   +13 more
doaj   +1 more source

Differences in clinical and imaging characteristics between p16-positive non-smokers and p16-positive smokers or p16-negative patients in oropharyngeal carcinoma

Scientific Reports, 2021
The eighth edition of the TNM classifies oropharyngeal squamous cell carcinomas (OSCCs) depending on p16 status. Some imaging features are reportedly associated more frequently with p16-positive (P16+) OSCC than p16-negative (p16−) OSCC.
Jean-Michel Trinh, Jacques Thomas, Julia Salleron, Philippe Henrot   +3 more
doaj   +1 more source

CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines

Scientific Reports, 2023
Pancreatic cancer is one of the most aggressive diseases with a very poor outcome. Olaparib, a PARP inhibitor, as maintenance therapy showed benefits in patients with metastatic pancreatic adenocarcinoma bearing germline BRCA1/2 mutations.
Andréa Witz, Julie Dardare, Aurélie Francois, Marie Husson, Marie Rouyer, Jessica Demange, Jean-Louis Merlin, Pauline Gilson, Alexandre Harlé   +8 more
doaj   +1 more source

177Lu-DOTA-0-Tyr3-octreotate infusion modeling for real-time detection and characterization of extravasation during PRRT

EJNMMI Physics, 2022
Purpose Given the recent and rapid development of peptide receptor radionuclide therapy (PRRT), increasing emphasis should be placed on the early identification and quantification of therapeutic radiopharmaceutical (thRPM) extravasation during ...
Christophe Mazzara, Julien Salvadori, Florian Ritzenthaler, Simon Martin, Clémence Porot, Alessio Imperiale   +5 more
doaj   +1 more source