Results 91 to 100 of about 6,619,981 (269)

Goodman Cancer Institute Research Symposium

McGill Journal of Medicine, 2022
Goodman Cancer Institute
doaj   +1 more source

Monitoring HSP70 exosomes in cancer patients’ follow up: a clinical prospective pilot study [PDF]

, 2020
Gaëtan Chanteloup, Marine Cordonnier, Nicolás Isambert, Aurélie Bertaut, Alice Hervieu, Audrey Hennequin, Maxime Luu, Sylvie Zanetta, Bruno Coudert, Leila Bengrine, Isabelle Desmoulins, Laure Favier, Aurélie Lagrange, P Pagès, Ivan M. Gutierrez, Jeanine Lherminier, Laure Avoscan, Clémentine Jankowski, Cédric Rébé, Angélique Chevriaux, Marie‐Martine Padeano, Charles Coutant, Sylvain Ladoire, Sylvain Causeret, Laurent Arnould, Céline Charon‐Barra, Vanessa Cottet, Julie Blanc, Christine Binquet, Marc Bardou, Carmen Garrido, Jessica Gobbo   +31 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Intensive Dose-Dense Compared With Conventionally Scheduled Preoperative Chemotherapy for High-Risk Primary Breast Cancer [PDF]

, 2009
Michael Untch, Volker Möbus, Walther Kuhn, B. R. Muck, Christoph Thomssen, Ingo Bauerfeind, Nadia Harbeck, Christoph Werner, Annette Lebeau, Andreas Schneeweiß, S. Kahlert, Franz Koch, Karl Ulrich Petry, D. Wallwiener, R. Kreienberg, Ute‐Susann Albert, Hans‐Joachim Lück, Axel Hinke, F. Jänicke, Gottfried E. Konecny   +19 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Adolescents' preferences for treatment decisional involvement during their cancer [PDF]

, 2015
Meaghann S. Weaver, Justin N. Baker, Jami S. Gattuso, Deborah Gibson, April Sykes, Pamela S. Hinds   +5 more
openalex   +1 more source

The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites [PDF]

, 2020
Sarah Libring, Aparna Shinde, Monica Chanda, Maryam Nuru, Heather Peshak George, Aya M. Saleh, Ammara Abdullah, Tamara L. Kinzer‐Ursem, Sarah Calve, Michael K. Wendt, Luis Solorio   +10 more
openalex   +1 more source

Characteristics and anatomic location of PD-1 ⁺ TCF1 ⁺ stem-like CD8 T cells in chronic viral infection and cancer [PDF]

, 2023
Se Jin Im, Rebecca C. Obeng, Tahseen H. Nasti, Daniel T. McManus, Alice O. Kamphorst, Sivaram Gunisetty, Nataliya Prokhnevska, Jennifer W. Carlisle, Ke Yu, Gabriel Sica, Lucas Esteves Cardozo, André N. A. Gonçalves, Haydn Kissick, Helder I. Nakaya, Suresh S. Ramalingam, Rafi Ahmed   +15 more
openalex   +1 more source