Results 91 to 100 of about 8,792,412 (290)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Cancers, 2018 Protein kinases are a large family of enzymes catalyzing protein phosphorylation. The human genome contains 518 protein kinase genes, 478 of which belong to the classical protein kinase family and 40 are atypical protein kinases [...]
Jonas Cicenas +3 more
openaire +5 more sources
Environmental management in Slovenian industrial enterprises - Empirical study
Management : Journal of Contemporary Management Issues, 2002 timulated with the firm belief that environmental management helps enterprises to achieve business success, expressed by a majority of managers in the sample enterprises, we present the results of an empirical study in the Slovene processing industry ...
Vesna Čančer
doaj
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Prostate cancer is not breast cancer
Indian Journal of Medical and Paediatric Oncology, 2016 AbstractCancers of the prostate and breast are hormone dependent cancers. There is a tendency to equate them and apply same algorithms for treatment. It is pointed out that metastatic prostate cancer with bone-only disease is a potentially fatal condition with a much poorer prognosis than metastatic breast cancer and needs a more aggressive approach.
openaire +4 more sources
Iodoterapia do Carcinoma Diferenciado da Tireóide
Revista Brasileira de Cancerologia, 2002 Protocolo de tratamento com iodo radioativo utilizado pelo INCA, elaborado em 1981, em conjunto com o Hospital dos Servidores do Estado, com algumas atualizações.
Instituto Nacional de Câncer
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Leucemias Agudas na Infância e Adolescência
Revista Brasileira de Cancerologia, 2001 Conduta diagnóstico-terapêutica do INCA para Leucemias Agudas na Infância e Adolescência.
Instituto Nacional de Câncer
doaj +1 more source
Breast tumor diagnosis in digital mammograms [PDF]
, 2019 Breast cancer has been classified as the most common cancer in most part of the world [1]. Breast cancer is caused by the growth of the abnormal cells in the breast. Breast cancer not only develops in women but also on men.
Gaik Tay, Kim +2 more
core +1 more source