Results 131 to 140 of about 9,858,231 (365)
Involvement of MicroRNA Families in Cancer [PDF]
, 2011 Collecting representative sets of cancer microRNAs (miRs) from the literature we show that their corresponding families are enriched in sets of highly interacting miR families.
Arjona, Dolores +3 more
core +5 more sources
Cancer or Not Cancer: That Is the Question
American Journal of Respiratory and Critical Care Medicine, 2023 Andrew Bush, Andrew G. Nicholson
openaire +2 more sources
Molecular Oncology, EarlyView.We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park +8 more
wiley +1 more source
Expert consensus of 177Lu-labeled PSMA radioligand therapy for clinical practice of prostate cancer (2024 edition) [PDF]
Zhongguo aizheng zazhi177Lu-labeled prostate-specific membrane antigen radioligand therapy (177Lu-PSMA-RLT) is an innovative treatment approach that precisely delivers β radiation emitted by 177Lu to prostate cancer cells, causing radiation damage to the tumor cells’ DNA and ...
Cancer Nuclear Medicine Committee of China Anti-Cancer Association, Chinese Association of Nuclear Medicine Physicians
doaj +1 more source
Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity. [PDF]
, 2014 A major impediment to the response of tumors to chemotherapy is that the large majority of cancer cells within a tumor are quiescent in G0/G1, where cancer cells are resistant to chemotherapy.
Bouvet, Michael +6 more
core +3 more sources
TRIM28 in cancer and cancer therapy
Frontiers in GeneticsTRIM28 (tripartite motif protein 28) was initially believed to be a transcription inhibitor that plays an important role in DNA damage repair (DDR) and in maintaining cancer cellular stemness. As research has continued to deepen, several studies have found that TRIM28 not only has ubiquitin E3 ligase activity to promote degradation of substrates, but ...
Kailang Li +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
The cellular ROS-scavenging function, a key factor determining the specific vulnerability of cancer cells to cold atmospheric plasma in vitro [PDF]
arXiv, 2017 Cold atmospheric plasma (CAP) has shown its promising application in cancer treatment both in vitro and in vivo. However, the anti-cancer mechanism is still largely unknown. CAP may kill cancer cells via triggering the rise of intracellular ROS, DNA damage, mitochondrial damage, or cellular membrane damage.
arxiv
Classification of Several Skin Cancer Types Based on Autofluorescence Intensity of Visible Light to Near Infrared Ratio [PDF]
, 2009 Skin cancer is a Malignant growth on the skin caused by many factors. The most common skin cancers are Basal Cell Cancer (BCC) and Squamous Cell Cancer (SCC).
Dwira, S. (Surya) +4 more
core
Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma
Molecular Oncology, EarlyView.Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley +1 more source