Results 121 to 130 of about 61,183 (295)

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Association between dietary fiber intake and cancer cachexia: mediation by inflammatory biomarkers

open access: yesFrontiers in Nutrition
BackgroundCancer cachexia (CC) is a major cause of death in cancer patients, with chronic inflammation being a key driver. Dietary fiber, a nutrient with strong anti-inflammatory potential, is closely linked to mortality risk in cancer patients. However,
Yan Guo   +16 more
doaj   +1 more source

Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
Background Cachexia is a multifactorial metabolic syndrome with high morbidity and mortality in patients with advanced cancer. The diagnosis of cancer cachexia depends on objective measures of clinical symptoms and a history of weight loss, which lag ...
Quan‐Jun Yang   +11 more
doaj   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane   +4 more
wiley   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Cancer cachexia [PDF]

open access: yes, 2021
Iñaki Eguren-Santamaría   +2 more
openaire   +2 more sources

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

open access: yesAdvanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin   +9 more
wiley   +1 more source

Clinical Impact of Cachexia in Head and Neck Cancer Patients Who Received Chemoradiotherapy

open access: yesCancer Management and Research, 2021
Naomi Hayashi,1 Yasuyoshi Sato,1 Yu Fujiwara,1,2 Naoki Fukuda,1 Xiaofei Wang,1 Kenji Nakano,1 Testuya Urasaki,1 Akihiro Ohmoto,1 Makiko Ono,1 Junichi Tomomatsu,1 Yukiko Sato,3 Hiroki Mitani,4 Takashi Toshiyasu,5 Shunji Takahashi1 1Department of Medical ...
Hayashi N   +13 more
doaj  

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

The Obesity Paradox in Cancer: Is Bigger Better?

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2022
Barry J.A. Laird, Richard J.E. Skipworth
doaj   +1 more source

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