Results 181 to 190 of about 3,014,693 (296)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

The role of PPARγ in cancer cachexia: friend or foe? [PDF]

Front Endocrinol (Lausanne)
Ding L, Jiang H, Shen L, Xu Y.
europepmc   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Otopetrin 1 protects against adipose tissue wasting during cancer cachexia progression. [PDF]

iScience
Li D, Yan X, Zhai W, He C, Li Z, Wang J, Huang D, Gu W, Shen X, Chen N.   +9 more
europepmc   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Liver-derived ceramides link metabolism to tissue wasting in cancer cachexia. [PDF]

J Clin Invest
Huang K, Perrimon N, Goncalves MD.
europepmc   +1 more source

B, N‐Co Doped Porous Carbon Nanotubes Supported Cu Single Atoms and B‐Doped Cu Nanoparticles for High‐Performance Electrocatalytic NO3RR and Zn‐Nitrate Batteries

Carbon Energy, EarlyView.
The ToC image shows a porous B, N‐doped carbon nanotube decorated with B‐doped Cu nanoparticles for nitrate‐to‐ammonia conversion. The unique structure enhances charge transport, promotes the adsorption and activation of key intermediates, alters the rate‐determining step, suppresses hydrogen evolution, and improves NH3 yield and Faradaic efficiency ...
Xiangding Li, Jiahui Xiang, Yilun Gao, Zhihao Liu, Haozhi Wang, Hua Yuan, Binbin Fan, Xiaoyu Huang   +7 more
wiley   +1 more source

Author Correction: Impaired cAMP-PKA-CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia. [PDF]

Nat Metab
Angelino E, Bodo L, Sartori R, Malacarne V, D'Anna B, Formaggio N, Barua S, Raiteri T, Lauria A, Reano S, Murabito A, Nicolau M, Ferrero F, Pezzini C, Rossino G, Favero F, Valmasoni M, Filigheddu N, Menga A, Corà D, Hirsch E, Oliviero S, Sartorelli V, Proserpio V, Ghigo A, Sandri M, Porporato PE, Talarico D, Caretti G, Graziani A.   +29 more
europepmc   +1 more source

Chemical engineering as an essential element of industrial biotechnology in Mexico: New aims in research and university education

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía, Octavio T. Ramírez, Rafael Vazquez‐Duhalt, Eduardo Bárzana   +3 more
wiley   +1 more source

Inhibition of ceramide synthesis ameliorates body wasting in a cancer cachexia model. [PDF]

J Clin Invest
Morigny P, Ji H, Cussonneau L, Zorzato S, Kwon Y, Riols F, Kaltenecker D, Maier A, Karthikaisamy V, Corrà S, Krauss T, Seeliger C, Gillani SQ, Tissink JJ, Lacas-Gervais S, Samanci TF, Maida A, Terron-Exposito R, Trinca A, von Toerne C, Nogara L, Claussnitzer M, Prokopchuk O, Bachmann J, Berriel Diaz M, Bindels LB, Kuda O, Hauner H, Haid M, Herzig S, Viscomi CF, Gilleron J, Zeigerer A, Blaauw B, Rohm M.   +34 more
europepmc   +1 more source