Results 141 to 150 of about 85,768 (307)

New Cardiovascular Biomarkers in Breast Cancer Patients Undergoing Doxorubicin-Based Chemotherapy. [PDF]

Arq Bras Cardiol, 2023
Pestana RMC, Silvino JPP, Oliveira AN, Soares CE, Sabino AP, Simões R, Gomes KB.   +6 more
europepmc   +1 more source

BRCAness and breast cancer: BRCAness y cáncer de mama

, 2021
Breast cancer constitutes the neoplasm of highest incidence, prevalence and mortality among women in western countries. Around 25-30% of these tumors are estrogen receptor (ER), progesterone receptor (PR) and HER2 negative. These tumors are called triple negative breast cancer (TNBC). TNBCs frequently appear in young patients.
openaire   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

[Construction and validation of a video about breast cancer for deaf womenConstrucción y validación de un video sobre el cáncer de mama para mujeres sordas]. [PDF]

Rev Cuid, 2023
Pereira-Gomes JD, Tomaz-De-Carvalho A, Sousa-Albuquerque-Brandao MG, Galindo-Neto NM, Do-Livramento-Fortes-Figueiredo M, Ribeiro Mariano-Grimaldi M.   +5 more
europepmc   +1 more source

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Study of influence of regulatory polymorphisms of expression in development of breast cancer [PDF]

, 2013
The human genome has millions of genetics variants that can affect gene expression. These variants are known as cis-regulatory variants and are responsible for intra-species phenotypic differences and individual susceptibility to disease.
Lopes, Joana Margarida Teixeira
core  

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Influência dos cancros ginecológicos e de mama no ajustamento conjugal [PDF]

, 2008
Tese de mestrado integrado em Psicologia (Psicologia Clínica e da Saúde - Núcleo de Saúde e Doença), apresentada à Universidade de Lisboa através da Faculdade de Psicologia e de Ciências da Educação, 2008Nesta investigação pretende-se avaliar a ...
Alves, Marta Carolina Cerqueira da Mota
core  

Sustainable Microwave‐Enhanced Synthesis of 2‐Substituted Benzofurans From o‐Alkynylanisoles in Acidic Deep Eutectic Solvents

European Journal of Organic Chemistry, EarlyView.
A microwave‐enhanced sustainable and versatile approach to substituted benzofurans from 2‐alkynylanisoles enabled by an active Brønsted acidic deep eutectic solvent. The research on alternative media for organic transformations remains a highly demanding topic.
Alessandra Gritti, Angelica Sita, Mehri Goudarzi, Stefano Fedeli, Elison Lepore, Donatella Nava, Matteo Tiecco, Alessandro Caselli, Valentina Pirovano, Giorgio Abbiati   +9 more
wiley   +1 more source

Análisis de detección temprana del cáncer de mama [PDF]

, 2018
[ES]El presente Trabajo de Fin de Grado trata, en primera instancia, de proporcionar una visión detallada sobre el cáncer de mama en mujeres, tanto a nivel mundial, como en Estados Unidos, España y País Vasco.
Ordiales Cuesta, Olatz
core