Results 221 to 230 of about 85,373 (307)

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Repercussions of the COVID-19 pandemic on breast cancer actions in a Brazilian state. [PDF]

Invest Educ Enferm
Dos Santos Dias PD, de Santana ME, de Azevedo Lima VL.   +2 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Temporal trend of breast cancer burden among younger and older Brazilian women, 1990-2019. [PDF]

Rev Bras Epidemiol
Santos TDS, Gonçalves CA, Cunha CPD, Milhomem JP, Silva KMD, Costa BTD, Piantolo RG, Fernandes RJC, Silva YMD, Guimarães RM.   +9 more
europepmc   +1 more source

Children of Divorced Parents—The Limitations of One‐Size‐Fits‐All Interventions

Child &Family Social Work, EarlyView.
ABSTRACT The political agenda of the Danish School Reform in 2014 provides a heightened awareness of pupils' mental health–including children of divorced parents. The primary focus is to support children's emotion management, and in that regard, conversation groups are offered to children experiencing divorce.
Pernelle Rose Hansen
wiley   +1 more source

[Meaning of the experience of breast cancer patients in a university clinic in Bogotá, Colombia: A qualitative study]. [PDF]

Rev Colomb Obstet Ginecol
Olivero Luna JD, Ramírez Flórez MC, Rozo Agudelo N, Rincón López JV, Castro Muñoz JA, Luna MF.   +5 more
europepmc   +1 more source

Centring Parent Voice: Exploring Popularized Parenting Posts to Understand Parents' Information and Support Needs

Child &Family Social Work, EarlyView.
ABSTRACT Despite the effectiveness of evidence‐based parenting programmes in improving parenting skills, reducing child maltreatment and promoting children's emotional and cognitive development, their impact is hindered by persistently low participation rates. At the same time, parents are increasingly turning online for parenting content.
Nehal Eldeeb, Jiwon Shin, Valerie B. Shapiro   +2 more
wiley   +1 more source

Content validity of guidance on self-care in the post-operative period for breast cancer. [PDF]

Rev Bras Enferm
Santos CPRSD, Goyanna NF, Corpes EF, Yanez RJV, Mourão Netto JJ, Barbosa RCM, Fernandes AFC.   +6 more
europepmc   +1 more source

“Simply Amazing and Fantastic”: The Maude Abbott Medical Museum Visitor Book, 2018–2023

Curator: The Museum Journal, EarlyView.
ABSTRACT The Maude Abbott Medical Museum has a collection of human remains which we believe is appropriate to preserve and use for teaching and research. We wondered to what extent our visitors feel the same way. We categorized all entries in our museum visitor book for 5 years into five groups based on specific words or phrases.
Rick Fraser
wiley   +1 more source