Results 31 to 40 of about 85,768 (307)

Prevalence of depression in patients with breast cancer [PDF]

, 2013
1.- INTRODUCCIÓN: La depresión es una sintomatología muy frecuente en los pacientes diagnosticados con cáncer de mama y su tratamiento. Se plantea una revisión de la literatura para analizar la prevalencia de la depresión en personas con cáncer de mama ...
Miguel Romeo, C., Sagardoy Muniesa, L., Sebastián Meneses, N.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dose dense versus 3 weekly AC during neoadjuvant chemoimmunotherapy for triple negative breast cancer

npj Breast Cancer
Neoadjuvant pembrolizumab plus chemotherapy (P + CT) has emerged as a standard of care for stage II-III triple-negative breast cancer (TNBC). However, the best anthracycline-cyclophosphamide (AC) schedule remains to be determined.
Renata Colombo Bonadio, Isadora Martins de Sousa, Flávia Cavalcanti Balint, Ana Carolina Marin Comini, Monique Celeste Tavares, Fernanda Madasi, Jose Bines, Rafael Dal Ponte Ferreira, Daniela Dornelles Rosa, Candice Lima Santos, Zenaide Silva de Souza, Daniele Assad-Suzuki, Júlio Antônio Pereira de Araújo, Débora de Melo Gagliato, Carlos Henrique dos Anjos, Bruna M. Zucchetti, Anezka Ferrari, Mayana Lopes de Brito, Renata Cangussu, Maria Marcela Fernandes Monteiro, Paulo M. Hoff, Laura Testa, Romualdo Barroso-Sousa   +22 more
doaj   +1 more source

É Possível Evitar a Biópsia do Linfonodo Sentinela em Pacientes com Câncer de Mama e Linfonodo Axilar Positivo com Resposta Patológica Completa à Quimioterapia Neoadjuvante?

Revista Brasileira de Cancerologia, 2023
Introdução: O câncer de mama representa 24,5% dos novos casos de neoplasias em mulheres no mundo. A quimioterapia neoadjuvante é uma importante ferramenta no tratamento dessa patologia, possibilita cirurgias menos agressivas na mama e axila, além de ...
Helano de Paula Gonçalves Souza, Francisco das Chagas Medeiros, Marcos Venício Alves Lima   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Efecto de las alteraciones genéticas, epigenéticas y expresión transcripcional de cadherina-E en la susceptibilidad al cáncer de mama

Biomédica: revista del Instituto Nacional de Salud, 2016
Introducción. La cadherina-E (CDH1) cumple un papel importante en la transición epitelio-mesénquima y está relacionada con la invasión y metástasis en varios tipos de carcinomas.
Andrés Felipe Aristizábal-Pachón, Catarina Satie Takahashi   +1 more
doaj   +1 more source

Conocimiento asociado con la práctica preventiva del cáncer de mama en estudiantes de enfermería

Horizonte Sanitario, 2023
Objetivo: Evaluar la asociación entre el conocimiento con la práctica y sus dimensiones sobre la prevención de cáncer de mama, en estudiantes del programa de estudios de Enfermería de la Universidad Católica Sedes Sapientiae, 2022.
Yonathan Josué Ortiz Montalvo, Daniela Carolina Vega Tapia, Maria Celeste Gonzales Paredes, Katherine Jenny Ortiz Romaní   +3 more
doaj   +1 more source

Desarrollo e implementación de guías para el aseguramiento de la calidad en el tamizaje de cáncer de mama: la experiencia europea [PDF]

, 2013
In Europe, as in many other regions of the world, breast cancer is a major cause of suffering and death. Early detection of breast cancer by systematic mammography screening can find lesions for which treatment is more effective and generally more ...
Arrossi, Silvina, von Karsa, Lawrence
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Aplicação da sequenciação de nova geração ao diagnóstico genético do cancro da mama hereditário [PDF]

, 2015
Introdução: O cancro da mama hereditário (CMH) constitui 5-10% dos casos de cancro da mama, dos quais cerca de 30% se devem a mutações germinais de elevada penetrância nos genes BRCA1 e BRCA2.
Gonçalves, João, Isidro, Glória, Pereira-Caetano, Iris, Rodrigues, Pedro, Silva, Catarina, Theisen, Patrícia I., Vieira, Luís   +6 more
core