Results 41 to 50 of about 85,768 (307)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Neoadjuvant pembrolizumab plus chemotherapy in older patients with early-stage triple-negative breast cancer: real-world insights from neo-real/GBECAM-0123

npj Breast Cancer
The KEYNOTE-522 regimen is the standard of care for stage II–III triple-negative breast cancer (TNBC). However, older patients were underrepresented in the pivotal trial.
Mariana Carvalho Gouveia, Romualdo Barroso-Sousa, Laura Lapuchesky, Laura Testa, Monique Celeste Tavares, Flávia Cavalcanti Balint, Carlos Henrique dos Anjos, Débora de Melo Gagliato, Mayana Lopes de Brito, Giuliana Colucci, Daniele Assad-Suzuki, Daniela Dornelles Rosa, Noele de Jesus Barros Gomes, Natalia Cristina Cardoso Nunes, Isadora Martins de Sousa, Matheus de Oliveira Andrade, Fernanda Madasi, Jose Bines, Mariana Savignano, Rafael Dal Ponte Ferreira, Candice Lima Santos, Maira Tavares, Mariana Ribeiro Monteiro, Zenaide Silva de Souza, Ana Maria Ulbricht Gomes, Bruna M. Zucchetti, Anezka Ferrari, Maria Marcela Fernandes Monteiro, Poliana Albuquerque Signorini, Solange Sanches, Paulo M. Hoff, Claudio Paletta, Maria del Pilar Estevez-Diz, Renata Colombo Bonadio   +33 more
doaj   +1 more source

Inequidades en salud: análisis sociodemográfico y espacial del cáncer de mama en mujeres de Córdoba, Argentina

Gaceta Sanitaria, 2017
Objetivo: Identificar determinantes sociodemográficos asociados a la distribución espacial de la incidencia de cáncer de mama en la provincia de Córdoba, Argentina, a fin de develar inequidades sociales en salud.
Natalia Tumas, Sonia Alejandra Pou, María del Pilar Díaz   +2 more
doaj   +1 more source

Câncer de mama masculino: contributos do enfermeiro na atenção primária de saúde

Revista Pró-UniverSUS, 2020
O câncer de mama é uma doença resultante da multiplicação de células anormais da mama, formando assim um tumor com o potencial para invadir outros órgãos.
Wanderson Alves Ribeiro, Ana Cristina Vieira da Silva, Denilson da Silva Evangelista   +2 more
doaj   +1 more source

Progestinas y cáncer de mama en terapia de reemplazo hormonal: cómo actúan y qué alternativas son más seguras

Revista Chilena de Obstetricia y Ginecología, 2022
En algunos estudios se ha asociado a la terapia de reemplazo hormonal (TRH) con estrógenos y progestinas a un mayor riesgo de cáncer de mama que la terapia con estrógenos solos.
Carla Bazán-Steffens, Óscar C. González   +1 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Afrontamiento y calidad de vida en pacientes con cáncer de mama. [PDF]

, 2009
150 p.El diagnóstico de cáncer de mama es la tercera causa de muerte por cáncer en la mujer Chilena, y constituye una de las situaciones de mayor carga y estrés emocional para quienes lo padecen.
Escobar Ponce, Francisca Paz, Ramos Alvarado, Nadia (Prof. Guía)   +1 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

CANCER DE MAMA EN CHILE: DATOS EPIDEMIOLOGICOS

Revista chilena de obstetricia y ginecología, 2002
The epidemiological analysis of breast cancer in Chile is described. The experience in the San Borja Arriarán Hospital is presented where an improved rate of precocions diagnosis is noted.
openaire   +3 more sources

The interdisciplinary of health technologies in the diagnosis and treatment of breast tumors: a case study [PDF]

, 2012
Introdução – O cancro de mama é a principal causa de morte por cancro na população feminina portuguesa. Assim, pretende-se descrever sucintamente o percurso de uma paciente com tumor de mama, evidenciando a interligação entre algumas áreas das ...
Coelho, Carina Marques, Machado, Carlos, Monsanto, Fátima, Moura, Filipe, Sá, Ana Cravo   +4 more
core