Results 111 to 120 of about 60,470 (301)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Evaluation of Neoadjuvant Chemotherapy Response in Patients with Locally Advanced Breast Cancer in Douala, Cameroon

open access: yesHealth Research in Africa
Introduction. Neoadjuvant chemotherapy is known to be effective in reducing the stage of locally advanced breast cancer. This study examines the response assessment of breast cancer patients to this therapy in Cameroon. Methodology.
Derliche Pamela Tonouo Wouoko   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Facteurs liés au diagnostic tardif du cancer du sein: expérience du CHU Mohammed VI Marrakech

open access: yesThe Pan African Medical Journal, 2015
Le cancer du sein est le premier cancer féminin en termes d'incidence et de mortalité. Au Maroc, il vient au premier rang des cancers de la femme avant celui du col utérin Il constitue un problème de santé publique.
Sofia Aloulou   +3 more
doaj   +1 more source

« Comment en parler? »: Création d’une simulation virtuelle sur les soins de santé sexuelle destinés aux survivantes du cancer du sein. [PDF]

open access: yesCan Oncol Nurs J, 2023
Silva A   +8 more
europepmc   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Le cancer en Mauritanie : résultats sur 10 ans du registre hospitalier de Nouakchott

open access: yesThe Pan African Medical Journal, 2013
Le fardeau du cancer reste mal connu en Mauritanie. Il n'est basé que sur des extrapolations de l'incidence des cancers des pays avoisinants. Les données du registre de l'hôpital national permettent de décrire les cas avec un diagnostic histologique ...
Nacer Dine Ould Mohamed Baba   +1 more
doaj   +1 more source

Fatalisme, méfiance et refus des traitements contre le cancer du sein au Ghana. [PDF]

open access: yesCan Oncol Nurs J, 2022
Salisu WJ   +4 more
europepmc   +1 more source

Gestion des symptômes en oncologie: quelles sont les interventions non-pharmacologiques permettant d'améliorer la gestion des nausées et vomissements chez les patients sous traitement de chimiothérapie ? [PDF]

open access: yes, 2017
Malgré l’avancement de la recherche médicale en oncologie, la chimiothérapie reste à ce jour le traitement le plus utilisé dans ce domaine de soin. Ce traitement provoque des effets indésirables tels que des nausées et vomissements.
Oberson, Magali   +2 more
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