Results 11 to 20 of about 3,425,228 (311)

ABO blood groups and liver cancer: prospective results from an HBsAg cohort study

open access: yesBMJ Open, 2021
Objective The association between ABO blood group and risk of liver cancer is unclear, although few studies have reported positive results. This study examined the relationship between ABO blood group and liver cancer in hepatitis B surface antigen ...
Jian Zhu   +8 more
doaj   +1 more source

The Involvement of TRIB3 and FABP1 and Their Potential Functions in the Dynamic Process of Gastric Cancer

open access: yesFrontiers in Molecular Biosciences, 2021
Background: Dysregulated expression of TRIB3 and FABP1 have been previously observed in human cancer tissues. However, there are little information as to their expression change in dynamic gastric diseases and the functional roles.Methods: Tissues from a
Songyi Liu   +20 more
doaj   +1 more source

MiR-1539 and Its Potential Role as a Novel Biomarker for Colorectal Cancer

open access: yesFrontiers in Oncology, 2021
PurposeWe investigated microRNA (miR) 1539 as a potential biomarker for predicting the risk and pathobiological behavior of colorectal cancer (CRC).MethodsOur strategy consisted of analyzing 100 serum samples from 51 CRC patients, 49 healthy controls ...
Xueyang Cui   +14 more
doaj   +1 more source

Key elements involved in Epstein–Barr virus-associated gastric cancer and their network regulation

open access: yesCancer Cell International, 2018
Background The molecular mechanism of Epstein–Barr virus (EBV)-associated gastric cancer (EBVaGC) remains elusive. A collection of molecular regulators including transcription factor and noncoding RNA (ncRNAs) may affect the carcinogenesis of EBVaGC by ...
Jing-jing Jing   +4 more
doaj   +1 more source

An Integrated Pan-Cancer Analysis of 33 Human Cancers Reveals the Potential Clinical Implications and Immunotherapeutic Value of C-X-C Motif Chemokine Ligand 13

open access: yesFrontiers in Oncology, 2022
BackgroundC-X-C Motif Chemokine Ligand 13 (CXCL13) plays a crucial part in the pathogenesis of numerous lymphoproliferative disorders, inflammatory responses, and autoimmune diseases.
Huanyu Zhang   +11 more
doaj   +1 more source

Pepsinogen C expression, regulation and its relationship with cancer

open access: yesCancer Cell International, 2017
Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as a zymogen PGC’s functions is unclear.
Shixuan Shen, Jingyi Jiang, Yuan Yuan
doaj   +1 more source

Clinical Assessment and Prognostic Evaluation of Tumor Markers in Patients with Gastric Cancer

open access: yesThe International Journal of Biological Markers, 2013
Aim To investigate the relationship between the serum levels of CEA, CA19-9, CA24-2, CA72-4, and AFP in patients with gastric cancer (GC) and their clinicopathological characteristics; to analyze the efficacy of these tumor markers in evaluating the ...
Jing Jiexian   +6 more
doaj   +1 more source

Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer

open access: yesJournal of Translational Medicine, 2023
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could affect cellular energy metabolism leading to ...
Ao-ran Liu   +7 more
doaj   +1 more source

HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach

open access: yesScientific Reports, 2017
Helicobacter pylori infection is the most important risk factor for gastric intestinal metaplasia (IM). Our previous study demonstrated that infection with H. pylori HpslyD-positive strains associated with IM.
Qiuping Li   +7 more
doaj   +1 more source

Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer

open access: yesCancer Cell International, 2017
Background Methylation plays an important role in the etiology and pathogenesis of colorectal cancer (CRC). This study aimed to identify aberrantly methylated-differentially expressed genes (DEGs) and pathways in CRC by comprehensive bioinformatics ...
Jingwei Liu   +5 more
doaj   +1 more source

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