Results 161 to 170 of about 5,215,493 (360)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Tongue squamous cell carcinoma treated by 5-aminolevulinic acid administrated through Microdrop method

Photodiagnosis and Photodynamic Therapy
Background: Postoperative recurrence of tongue squamous cell carcinoma (TSCC) has always been a clinical problem for patients and doctors. Surgery and radiotherapy are the main treatment methods for TSCC, but reoperation often leads to functional ...
Yong Zhang, Anqi Lyu, Fang Zhang, Lingdi Zhao, Baozhen Ma, Quanli Gao   +5 more
doaj   +1 more source

The blockade of immune checkpoints in cancer immunotherapy

Nature Reviews. Cancer, 2012
D. Pardoll
semanticscholar   +1 more source

HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]

, 2010
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C, Linley, AJ, Mathieu, MG, McArdle, SEB, Reeder, SP, Rees, RC, Tartour, E   +6 more
core  

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Nature Medicine, 2018
Peng Jiang, Shengqing Gu, D. Pan, Jingxin Fu, A. Sahu, Xihao Hu, Ziyi Li, Nicole Traugh, Xia Bu, Bo Li, Bo Li, Jun Liu, G. Freeman, Myles A. Brown, K. Wucherpfennig, X. Liu   +15 more
semanticscholar   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy

OncoImmunology
Activins, members of the TGF-beta superfamily, have been isolated and identified in the endocrine system, but have not been substantially investigated in the context of the immune system and endocrine-unrelated cancers.
Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll   +9 more
doaj   +1 more source

Neoantigens in cancer immunotherapy

Science, 2015
T. Schumacher, R. Schreiber
semanticscholar   +1 more source

Immunotherapy at any line of treatment improves survival in patients with advanced metastatic non‐small cell lung cancer (NSCLC) compared with chemotherapy (Quijote‐CLICaP) [PDF]

, 2019
Alejandro Ruíz-Patiño, Óscar Arrieta, Andrés F. Cardona, Claudio Martín, Luis E. Raez, Zyanya Lucía Zatarain-Barrón, Feliciano Barrón, Luisa Ricaurte, M.A. Bravo-Garzón, Luís Más, Luis Corrales, Leonardo Rojas, Lorena Lupinacci, Florencia Perazzo, Carlos Bas, Omar Carranza, Carmen Puparelli, Manglio Rizzo, Rossana Ruiz, Christian Rolfo, Pilar Archila, July Rodríguez, Carolina Sotelo, Carlos Vargas, Hernán Carranza, Jorge Otero, Luís Pino, Carlos Ortíz, Paola Laguado, Rafael Rosell, on behalf of the CLICaP   +30 more
openalex   +1 more source