Results 181 to 190 of about 482,699 (357)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Induction of tissue-specific autoimmune prostatitis with prostatic acid phosphatase immunization: implications for immunotherapy of prostate cancer. [PDF]

, 1997
Lawrence Fong, Curtis Ruegg, Dirk G. Brockstedt, E G Engleman, Reiner Laus   +4 more
openalex   +1 more source

Stealth transgenes enable CAR-T cells to evade host immune responses

Journal for ImmunoTherapy of Cancer
Background Adoptive cell therapy, such as chimeric antigen receptor (CAR)-T cell therapy, has improved patient outcomes for hematological malignancies.
David Millar, Rebecca Larson, Marcela V Maus, Amanda A Bouffard, Matthew J Frigault, Stefanie R Bailey, Mark B Leick, Michael C Kann, Cameron J Turtle, Trisha Berger, Kathleen Gallagher, Korneel Grauwet, Harrison Silva   +12 more
doaj   +1 more source

Cancer immunotherapy

Chinese Journal of Cancer, 2014
Yan, Li, Chen, Helen X.
openaire   +2 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

IMMUNOTHERAPY FOR GASTROINTESTINAL CANCER PATIENTS WITH BCG-CWS ADMINISTERED INTRATUMORALLY BEFORE OPERATION

, 1980
Hiroaki Miwa, Minoru Moriyama, Fumio Ono, Osamu Hashimoto, Tsutomu Kobayashi, Tetsuhide OKA, Takashi Kitagawa, Kenji Nakamura, T Mannami, Eiji KONAGA, Kunzo Orita   +10 more
openalex   +2 more sources

Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts. [PDF]

, 1995
Laurence Zitvogel, Hideaki Tahara, Paul D. Robbins, Walter J. Storkus, Martha Clarke, Michael A. Nalesnik, Michael T. Lotze   +6 more
openalex   +1 more source

Clustering and Meta-Analysis Using a Mixture of Dependent Linear Tail-Free Priors [PDF]

arXiv
We propose a novel nonparametric Bayesian approach for meta-analysis with event time outcomes. The model is an extension of linear dependent tail-free processes. The extension includes a modification to facilitate (conditionally) conjugate posterior updating and a hierarchical extension with a random partition of studies. The partition is formalized as
arxiv  

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

Advanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang, Xin Zhang, Denghui Xie, Chunying Chen, Zhifeng Huang, Zhong Alan Li   +5 more
wiley   +1 more source

Harnessing Preference Optimisation in Protein LMs for Hit Maturation in Cell Therapy [PDF]

arXiv
Cell and immunotherapy offer transformative potential for treating diseases like cancer and autoimmune disorders by modulating the immune system. The development of these therapies is resource-intensive, with the majority of drug candidates failing to progress beyond laboratory testing.
arxiv