Results 221 to 230 of about 348,034 (261)
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Cancer immunotherapy – revisited
Nature Reviews Drug Discovery, 2011Our insight into antitumour immune responses has increased considerably during the past decades, yet the development of immunotherapy as a treatment modality for cancer has been hampered by several factors. These include difficulties in the selection of the optimal dose and schedule, the methods of evaluation, and financial support.
John Haanen, , Lesterhuis W Joost
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Biotechnology Journal, 2006
AbstractCancer is the second leading cause of death in the industrialized world. Most cancer patients are treated by a combination of surgery, radiation and/or chemotherapy. Whereas the primary tumor can, in most cases, be efficiently treated by a combination of these standard therapies, preventing the metastatic spread of the disease through ...
Manfred, Schuster +2 more
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AbstractCancer is the second leading cause of death in the industrialized world. Most cancer patients are treated by a combination of surgery, radiation and/or chemotherapy. Whereas the primary tumor can, in most cases, be efficiently treated by a combination of these standard therapies, preventing the metastatic spread of the disease through ...
Manfred, Schuster +2 more
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Veterinary Clinics of North America: Small Animal Practice, 2019
The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
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The enhanced understanding of immunology experienced over the last 4 decades afforded through the tools of molecular biology has recently translated into cancer immunotherapy becoming one of the most exciting and rapidly expanding fields. Human cancer immunotherapy is now recognized as one of the pillars of treatment alongside surgery, radiation, and ...
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New England Journal of Medicine, 1977
Control of cancer by immunologic methods was first suggested by physicians who observed, more than a century ago, that advanced cancer occasionally underwent total regression after acute bacterial ...
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Control of cancer by immunologic methods was first suggested by physicians who observed, more than a century ago, that advanced cancer occasionally underwent total regression after acute bacterial ...
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Annals of the New York Academy of Sciences, 1999
Abstract: The goal of cancer treatment is to develop modalities that specifically target tumor cells, thereby avoiding unnecessary side effects to normal tissue. Vaccine strategies that result in the activation of the immune system specifically against proteins expressed by a cancer have the potential to be effective treatment for this purpose.
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Abstract: The goal of cancer treatment is to develop modalities that specifically target tumor cells, thereby avoiding unnecessary side effects to normal tissue. Vaccine strategies that result in the activation of the immune system specifically against proteins expressed by a cancer have the potential to be effective treatment for this purpose.
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Complement in Cancer and Cancer Immunotherapy
Archivum Immunologiae et Therapiae Experimentalis, 2011Recently, there has been an increase of interest in the use of biological or immune-based therapies for patients with malignancies. This has been informed by the deeper understanding of the crosstalk between the host immune system and malignant tumours, as well as the potential advantages of immunotherapy-high specificity and less toxicity compared to ...
Martin, Kolev +2 more
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Bioinformatics for Cancer Immunotherapy
2020Our immune system plays a key role in health and disease as it is capable of responding to foreign antigens as well as acquired antigens from cancer cells. Latter are caused by somatic mutations, the so-called neoepitopes, and might be recognized by T cells if they are presented by HLA molecules on the surface of cancer cells.
Christoph, Holtsträter +3 more
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Neoantigens in cancer immunotherapy
Science, 2015The clinical relevance of T cells in the control of a diverse set of human cancers is now beyond doubt. However, the nature of the antigens that allow the immune system to distinguish cancer cells from noncancer cells has long remained obscure. Recent technological innovations have made it possible to dissect the immune response to patient-specific ...
Ton N, Schumacher, Robert D, Schreiber
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Immunotherapy for Prostate Cancer
Current Pharmaceutical Design, 2006The absence of curative therapies for advanced or recurrent forms of prostate cancer has prompted a vigorous search for novel treatment strategies. Immunotherapy encompasses one particularly promising systemic approach to treat prostate cancer. Immune-based strategies to treat prostate cancer have recently been facilitated by the identification of a ...
R Jeffrey, Karnes +2 more
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Immunotherapy in colorectal cancer
Scandinavian Journal of Gastroenterology, 2009Udgivelsesdato ...
Burgdorf, Stefan K +2 more
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