Results 271 to 280 of about 5,215,493 (360)

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

The role of gut mycobiome in responses to cancer immunotherapy. [PDF]

Gut Microbes
Szóstak N, Kozłowski P, Zuo T, Philips A.   +3 more
europepmc   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Harnessing the Microbiome in Cancer Immunotherapy: Regulation, Prediction, and Therapeutic Targeting. [PDF]

Annu Rev Immunol
Zarour HM, Trinchieri G.
europepmc   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source

Tumor Microenvironment-Responsive Nanomedicines for Potentiating Cancer Immunotherapy. [PDF]

Adv Sci (Weinh)
Huang Q, Tong F, Chen J, Kayumov M, Lv Y, Shi Y, Ye B, Gao H.   +7 more
europepmc   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

Triplet RNA Lipid Nanoparticles for Locoregional Cancer Immunotherapy. [PDF]

Small Sci
Walters AA, Qin Y, Saleh AF, Cheung CCL, Lyu Q, Zhu Z, Gafar HAM, Tzu-Wen Wang J, Al-Jamal KT.   +8 more
europepmc   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Special Issue: Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy. [PDF]

Int J Mol Sci
Galati D.
europepmc   +1 more source