Results 141 to 150 of about 932,314 (264)

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Female cancer incidence before and after diagnosis of primary Sjögren's disease: A retrospective cohort study. [PDF]

J Transl Autoimmun
Sjöström B, Bredberg A, Olsson P, Ullén S, van der Stoep JH, Henriksson G.   +5 more
europepmc   +1 more source

High‐Throughput In Vivo Subcellular Analysis of Gold Nanoparticles for Tumor Mitochondrial Targeting

Advanced Materials, EarlyView.
A DNA barcoding system enables high‐throughput in vivo screening of mitochondrial‐targeting gold nanoparticles. Thirty nanoparticle types with varied shapes, sizes, and ligands are individually barcoded and pooled. The pooled library is administered to tumor‐bearing mice, and barcodes retrieved from tumor mitochondria are amplified and sequenced to ...
Xingyue Huang, Xuehao Tian, Kuei Chen, Yang Wu, ChenCheng Xue, Yingjie Quek, Jessalyn Low, Arun Kumar, Andy Tay   +8 more
wiley   +1 more source

Cancer incidence, stage at diagnosis, and trends across the Navajo Nation, 2014-2018. [PDF]

Cancer
Yazzie D, Pete D, Briscoe C, Jim MA, Meisner A, Wiggins C, Doyle D, Yee G, Goldtooth C, Sanderson PR, Keene CN, Smith M, Sehn H, Damon S, Kettering CL, Emerson M, Curley C, Bea J, Yazzie S, Joe N, Doherty J, Dirk de Heer H, Navajo Cancer Workgroup.   +22 more
europepmc   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Stage-specific and regional trends in prostate cancer incidence in Kazakhstan, 2005-2024. [PDF]

Front Oncol
Igissinova G, Igissin N, Kudaibergenova I, Yermek N, Telmanova Z, Turebayev D, Jexenova A, Moldagali R, Khairli G, Kazhitaev A, Dyakov S, Baibosynov D, Shishkin I, Nogoibaeva K, Baytelieva A, Mamatov N, Halimi A, Bilyalova Z.   +17 more
europepmc   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

Advanced Materials, EarlyView.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Editorial: Recently Identified Global Trends in Cancer Incidence and Mortality and Modifiable Cancer Risk Factors. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

Residential proximity to nuclear power plants and cancer incidence in Massachusetts, USA (2000-2018). [PDF]

Environ Health
Alwadi Y, Evans JS, Schwartz J, Vieira CLZ, Christiani DC, Coull BA, Koutrakis P.   +6 more
europepmc   +1 more source