Results 251 to 260 of about 7,013,774 (312)

Rational Design of Organic Chromophores for Simultaneously Trig‐gering Redox Imbalance and Tracking Organelles in Biological Sys‐tems Under Near‐Infrared Light Irradiation

Advanced Healthcare Materials, EarlyView.
TOC represents the synthesis of theory‐guided novel near‐infrared (NIR) light‐absorbing organic photosensitizers (OPS) enabling redox‐induced tumor phototherapy and single‐cell organelle tracking. ABSTRACT The design of organic photosensitizers that operate efficiently in the near‐infrared (NIR) region remains challenging due to the need to balance ...
Pragti, Bidyut Kumar Kundu, Jiajie Diao, Yujie Sun   +3 more
wiley   +1 more source

Reprogramming of cancer metabolism via photoresponsive nano-PROTAC enhances pyroptosis-mediated immunotherapy. [PDF]

Signal Transduct Target Ther
Park B, Choi J, Lee JH, Kim Y, Lee W, Lee A, Sun IC, Yoon HY, Kim Y, Kim SH, Yang Y, Kim K, Park J, Shim MK.   +13 more
europepmc   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Exploratory Insights into Gastric Cancer Metabolism Through Amino Acid and Acylcarnitine Profiling in Plasma Samples. [PDF]

Biomedicines
Ursu Ș, Ursu CP, Bogos LG, Pralea IE, Moldovan RC, Zaharie F, Spârchez Z, Ciocan RA, Pop RS, Bodea CI, Gherman CD, Iuga CA, Al Hajjar N.   +12 more
europepmc   +1 more source

A 3D‐Printed Vascular‐Like Perfusion Tumor‐on‐a‐Chip Recapitulates High‐Grade Breast Cancer With in Vivo‐Relevant Drug Resistance

Advanced Healthcare Materials, EarlyView.
A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee, Bingjie Sun, Nicholas X. Fang, Chunguang Xia   +3 more
wiley   +1 more source

Senolytic-sensitive p16^Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity. [PDF]

Cell Stem Cell
Lee JY, Reyes N, Woo SH, Allen NC, Kadota T, Lechner A, Biswas R, Goel S, Stratton F, Kuang C, Tsukui T, Auyeung V, Mansfield AS, LaFave LM, Peng T.   +14 more
europepmc   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Branched-chain amino acid and cancer: metabolism, immune microenvironment and therapeutic targets. [PDF]

J Transl Med
Xiong H, Liu R, Xu K, Chen X, Huang L, Shou Y, Huang Y, Sheng H, Lu Y, Zhang H.   +9 more
europepmc   +1 more source

Targeting cancer metabolism through p-cresol mediated Inhibition of pyruvate dehydrogenase kinase 3 in lung cancer. [PDF]

Sci Rep
Ashames A, Anwar S, Sulaimani MN, Pinky, Khan MS, Shahwan M, Parvez S, Hassan MI, Dinislam K, Shamsi A.   +9 more
europepmc   +1 more source

The Role of Stroma in Cancer Metabolism. [PDF]

Cold Spring Harb Perspect Med
Kimmelman AC, Sherman MH.
europepmc   +1 more source