Results 101 to 110 of about 4,194,562 (264)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Diabetes alone should not be a reason for withholding adjuvant chemotherapy for stage III colon cancer [PDF]

, 2011
Background: With increasing prevalence of diabetes mellitus and colon cancer, the number of patients suffering from both diseases is growing, and physicians are being faced with complicated treatment decisions.
Wouter M. W. Dercksen, Extermann, Martine, Harm R. Haak, Janssen-Heijnen, Maryska L.G., van de Schans, Saskia A.M., Haak, Harm R., Dercksen, Wouter M.W., Maren A. van Waalwijk, Martine Extermann, van Waalwijk, Maren A., Saskia A. M. van de Schans, Maryska L. G. Janssen-Heijnen   +11 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

All Ireland cancer statistics: second report: A collaborative report by the Northern Ireland Cancer Registry and the National Cancer Registry (Ireland): A profile of cancer incidence, mortality and survival for the island of Ireland, 1998-2000 [PDF]

, 2004
These are highlights from the second collaborative report produced by the Northern Ireland Cancer Registry and the National Cancer Registry (Ireland). Data from both registries have been merged and integrated to profile and assess the cancer incidence
National Cancer Registry Ireland (NCRI)
core  

Breast cancer survival in England, Norway and Sweden: a population-based comparison.

, 2010
Several international studies have found that survival from breast cancer is lower in the United Kingdom than in some other European countries. We have compared breast cancer survival between the national populations of England, Norway and Sweden, with a
Sandin, Fredrik,, Purushotham, Arnie, Purushotham, Arnie; id_orcid, Holmberg, Lars, Holmberg, Lars,, Møller, Henrik, Sandin, Fredrik, Linklater, Karen M., Klint, Asa, Möller, Henrik, Moller, Henrik; id_orcid, Linklater, Karen M, Robinson, David, Bray, Freddie   +13 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

The association between polychlorinated dibenzo-p-dioxin exposure and cancer mortality in the general population: a cohort study

Frontiers in Public Health
IntroductionEarlier research has indicated that being exposed to polychlorinated dibenzo-p-dioxins (PCDDs) in the workplace can heighten the likelihood of cancer-related deaths.
Lei Zheng, Xianli Zhang, Zhe Gao, Chunyu Zhong, Dezhi Qiu, Qing Yan   +5 more
doaj   +1 more source

Mortality by cancer as a function of age [PDF]

Experientia, 1953
Le logarithme de la mortalite par cancer, entre la puberte et la vieillesse, est une fonction presque lineaire de l'âge. La mortalite est doublee tous les 6,3 ans. Cette progression nous mene a la conception que la sensibilite au cancer serait determinee par la concentration d'un facteur materiel qui se reproduit.
openaire   +2 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer [PDF]

, 2013
<p>Background: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)–extracellular signal-regulated protein kinase 5 (ERK5)-mediated signalling has been implicated in a number of tumour types including prostate cancer (CaP). The mechanism
Kalna, G., Yang, Z H, Z H Yang, Leung, H.Y., Scardino, P, L B Singh, Singh, LB, H Møller, C Cooper, Cuzick, J, J Fleming, Singh, L.B., Yang, Z.H., I Ahmad, G Kalna, D M Berney, Singh, L. B., Scardino, P., Leung, H Y, Ahmad, I., Møller, H; id_orcid, J Cuzick, Berney, D. M., Cuzick, J., Møller, H., Leung, H. Y., Berney, DM, Fisher, G., Fleming, J., Cooper, C., Leung, HY, Kalna, G, P Scardino, Yang, Z. H., Berney, D.M., Fisher, G, Cooper, C, Møller, H, Ahmad, I, G Fisher, Yang, ZH, Singh, L B, Fleming, J, H Y Leung, Berney, D M   +44 more
core   +1 more source