Results 241 to 250 of about 6,321,039 (371)

Defining Spine Cancer Pain Syndromes: A Systematic Review and Proposed Terminology. [PDF]

open access: yesGlobal Spine J
Pahuta M   +18 more
europepmc   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

NFAT1 Signaling Contributes to Bone Cancer Pain by Regulating IL-18 Expression in Spinal Microglia. [PDF]

open access: yesCNS Neurosci Ther
Chen X   +14 more
europepmc   +1 more source

The dose—Response relationship of controlled-release codeine (Codeine Contin) in chronic cancer pain

open access: bronze, 1994
Srini Chary   +5 more
openalex   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

open access: yesAdvanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi   +12 more
wiley   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

open access: yesAdvanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic   +20 more
wiley   +1 more source

GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability. [PDF]

open access: yesAdv Sci (Weinh)
Wang K   +10 more
europepmc   +1 more source

Harmonising Hope: Impact of Music Therapy on Cancer Pain and Palliative Care. [PDF]

open access: yesIndian J Palliat Care
Jethva DD   +5 more
europepmc   +1 more source

Correlation of patient and caregiver ratings of cancer pain

open access: hybrid, 1991
Stuart A. Grossman   +4 more
openalex   +1 more source

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