Results 141 to 150 of about 3,398,816 (318)

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

open access: yesAdvanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti   +4 more
wiley   +1 more source

Cancer incidence projections for Ireland 2020-2045

open access: yes, 2019
The most recent annual statistical report of the National Cancer Registry, published in November 2018, provided a summary of projected changes in the cancer incidence burden in Ireland over the coming decades, up to 2045.
National Cancer Registry Ireland (NCRI)
core  

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

open access: yesAdvanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu   +7 more
wiley   +1 more source

Patient voice in cancer research: patient workshop and discussion groups.

open access: yes, 2019
The National Cancer Strategy 2017-2026 sets out the vision for delivery of cancer services in Ireland. Central to the strategy is that services be in place to better serve the needs of cancer patients.
National Cancer Registry Ireland (NCRI)
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer

open access: yesScientific Reports
Breast cancer (BC) is a heterogeneous disease, traditionally classified by hormone receptor and HER2 (human epidermal growth factor receptor 2) status. HER2-low, characterized by low HER2 expression without gene amplification, recently gained attention ...
Maria Elena Lacruz   +10 more
doaj   +1 more source

Annual report and accounts for year ending 31 December 2013 - National Cancer Registry [PDF]

open access: yes, 2014
The statutory duties of the National Cancer Registry include a requirement “to promote and facilitate the use of the data...in approved research projects and in the planning and management of services”. This obligation has been discharged though making
National Cancer Registry Ireland (NCRI)
core  

A European collaborative initiative to systematically map cancer risk by migration background: the Cancer RADAR project

open access: yesInternational Journal for Equity in Health
Background The World Health Organization (WHO) Action Plan for Refugee and Migrant Health highlights the need for strengthened migration health governance and data-informed policies. A major barrier in Europe has been the lack of systematically collected
Catharina Johanna Alberts   +19 more
doaj   +1 more source

Cancer Trends: Childhood cancer

open access: yes, 2017
This is the second trends report NCRI has published on childhood cancers, updating a previous report covering 1994-20111. To facilitate summary of the amount and complexity of material included, presentation and layout has been in general retained from ...
National Cancer Registry Ireland (NCRI)
core  

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

open access: yesAdvanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu   +12 more
wiley   +1 more source

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