Results 1 to 10 of about 1,708,228 (211)
Colorectal cancer (CRC) has two major subtypes, microsatellite instability (MSI) and microsatellite stability (MSS) based on the genomic instability. In this study, using computational programs, we identified 9 master transcription factors (TFs) based on
Qian Yang +4 more
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Guide to Metabolomics Analysis: A Bioinformatics Workflow
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The key purpose of metabolomics is to identify the metabolites corresponding to each biological phenotype, and then provide an analysis of the mechanisms involved ...
Yang Chen, En-Min Li, Li-Yan Xu
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Alterations of RNA splicing patterns in esophagus squamous cell carcinoma
Alternative splicing (AS) is an important biological process for regulating the expression of various isoforms from a single gene and thus to promote proteome diversity.
Jiyu Ding +13 more
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Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is one of the world’s leading causes of death, and its primary clinical therapy relies on surgical resection, chemotherapy, radiotherapy, and chemoradiotherapy.
Zhen-Yuan Zheng +10 more
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Annexin A3, a Calcium-Dependent Phospholipid-Binding Protein: Implication in Cancer
Annexin A3 (ANXA3), also known as lipocortin III and placental anticoagulant protein III, has been reported to be dysregulated in tumor tissues and cancer cell lines, and harbors pronounced diagnostic and prognostic value for certain malignancies, such ...
Liu Yang +4 more
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Cancer incidence in hypertensives [PDF]
Cancer incidence was measured over a 5-year period (1978 to 1982) in 4067 hypertensive patients, and 10,366 normotensive patients from general practices in southwestern Ontario. For cancer of all sites an elevated incidence was found among hypertensive patients.
C, Buck, A, Donner
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Longitudinal trends in prostate cancer incidence, mortality, and survival of patients from two Shanghai city districts: a retrospective population-based cohort study, 2000-2009. [PDF]
BackgroundProstate cancer is the fifth most common cancer affecting men of all ages in China, but robust surveillance data on its occurrence and outcome is lacking. The specific objective of this retrospective study was to analyze the longitudinal trends
Deng, Haiju +5 more
core +7 more sources
ObjectiveLimiting purine intake, inhibiting xanthine oxidoreductase (XOR) and inhibiting urate reabsorption in proximal tubule by uricosuric drugs, to reduce serum uric acid (UA) levels, are recognized treatments for gout.
Huanhuan Wang +9 more
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THE AGE INCIDENCE OF CANCER. [PDF]
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Roberts, R. E., Wilson, ArthurC
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Proteomics can aid in the identification of molecular subtypes in cancers. Here, the authors perform proteomic profiling of 124 paired oesophageal cancer and adjacent non-tumour tissues and identify two subtypes that are associated with patient survival ...
Wei Liu +23 more
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