Results 11 to 20 of about 1,708,228 (211)

A 15-Gene Signature and Prognostic Nomogram for Predicting Overall Survival in Non-Distant Metastatic Oral Tongue Squamous Cell Carcinoma

Frontiers in Oncology, 2021
BackgroundOral tongue squamous cell carcinoma (OTSCC) is a devastating tumor with poor prognosis. There is an urgent need for reliable biomarkers to help predict prognosis and guide treatment for OTSCC.
Muyuan Liu, Litian Tong, Bin Liang, Xuhong Song, Lingzhu Xie, Hanwei Peng, Dongyang Huang, Dongyang Huang   +7 more
doaj   +1 more source

Co-Expression of Chromatin Assembly Factor 1 Subunit A and Proliferating Cell Nuclear Antigen Is a Prognostic Biomarker of Esophageal Cancer

Biomedicines, 2023
(1) Background: Esophageal cancer (EC) is an important global health challenge. Due to the lack of necessary biomarkers and therapeutic targets, the survival of EC patients is poor.
Bing Wen, Dan-Xia Deng, Lian-Di Liao, Zhi-Da Zhang, Ya-Qi Zheng, Ke Dong, Li-Yan Xu, En-Min Li   +7 more
doaj   +1 more source

P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer

Cancer Communications, 2021
Background Fascin is crucial for cancer cell filopodium formation and tumor metastasis, and is functionally regulated by post‐translational modifications. However, whether and how Fascin is regulated by acetylation remains unclear.
Yin‐Wei Cheng, Fa‐Min Zeng, Da‐Jia Li, Shao‐Hong Wang, Jian‐Zhong He, Zhen‐Chang Guo, Ping‐Juan Nie, Zhi‐Yong Wu, Wen‐Qi Shi, Bing Wen, Xiu‐E Xu, Lian‐Di Liao, Zhi‐Mao Li, Jian‐Yi Wu, Jun Zhan, Hong‐Quan Zhang, Zhi‐Jie Chang, Kai Zhang, Li‐Yan Xu, En‐Min Li   +19 more
doaj   +1 more source

Emerging cancer incidence, mortality, hospitalisation and associated burden among Australian cancer patients, 1982 - 2014: an incidence-based approach in terms of trends, determinants and inequality [PDF]

, 2019
Objective Cancer is a leading killer worldwide, including Australia. Cancer diagnosis leads to a substantial burden on the individual, their family and society.
Alam, Khorshed, Dunn, Jeff, Gow, Jeff, Mahumud, Rashidul Alam   +3 more
core   +2 more sources

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment

Nature Communications, 2021
The microenvironment of oesophageal squamous cell carcinomas (ESCC) is heterogeneous and can strongly impact response to treatment. Here, the authors characterize the ESCC tumour microenvironment with single-cell RNA-seq, finding CST1 + myofibroblasts ...
Huy Q. Dinh, Feng Pan, Geng Wang, Qing-Feng Huang, Claire E. Olingy, Zhi-Yong Wu, Shao-Hong Wang, Xin Xu, Xiu-E Xu, Jian-Zhong He, Qian Yang, Sandra Orsulic, Marcela Haro, Li-Yan Li, Guo-Wei Huang, Joshua J. Breunig, H. Phillip Koeffler, Catherine C. Hedrick, Li-Yan Xu, De-Chen Lin, En-Min Li   +20 more
doaj   +1 more source

Worldwide malaria incidence and cancer mortality are inversely associated [PDF]

, 2018
BACKGROUND: Investigations on the effects of malaria infection on cancer mortality are limited except for the incidence of Burkitt’s lymphoma (BL) in African children.
Liu, P.
core   +1 more source

Aberrant activation of CYR61 enhancers in colorectal cancer development

Journal of Experimental & Clinical Cancer Research, 2019
Background High expression of secreted matricellular protein cysteine-rich 61 (CYR61) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation has been shown to correlate with expression of key genes involved in cancer ...
Lingzhu Xie, Xuhong Song, Hao Lin, Zikai Chen, Qidong Li, Tangfei Guo, Tian Xu, Ting Su, Man Xu, Xiaolan Chang, Long-Kun Wang, Bin Liang, Dongyang Huang   +12 more
doaj   +1 more source

Effects of reproductive and demographic changes on breast cancer incidence in China: A modeling analysis [PDF]

, 2008
Background: Breast cancer incidence is currently low in China. However, the distribution of reproductive and lifestyle risk factors for breast cancer among Chinese women is changing rapidly.
Colditz, Graham A., Gao, Yu-Tang, Hesketh, Therese, Linos, Eleni, Linos, Katerina, Qu, Jian Ding, Rosner, Bernard A., Spanos, Demetri, Zheng, Wei   +8 more
core   +1 more source

Resveratrol induces autophagy-dependent apoptosis in HL-60 cells

BMC Cancer, 2018
Background All known mechanisms of apoptosis induced by resveratrol act through cell cycle arrest and changes in mitochondrial membrane potential. It is currently unknown whether resveratrol-induced apoptosis is associated with other physiological ...
Yingying Fan, Jen-Fu Chiu, Jing Liu, Yan Deng, Cheng Xu, Jun Zhang, Guanwu Li   +6 more
doaj   +1 more source

Joint disease mapping using six cancers in the Yorkshire region of England [PDF]

, 2008
OBJECTIVES: The aims of this study were to model jointly the incidence rates of six smoking related cancers in the Yorkshire region of England, to explore the patterns of spatial correlation amongst them, and to estimate the relative weight of smoking ...
Downing, A., Edwards, K.L., Forman, D., Gilthorpe, G.S., Manda, S.O.M.   +4 more
core   +3 more sources