Results 21 to 30 of about 1,708,228 (211)

Protein-coding genes combined with long noncoding RNA as a novel transcriptome molecular staging model to predict the survival of patients with esophageal squamous cell carcinoma

Cancer Communications, 2018
Background Esophageal squamous cell carcinoma (ESCC) is the predominant subtype of esophageal carcinoma in China. This study was to develop a staging model to predict outcomes of patients with ESCC.
Jin-Cheng Guo, Yang Wu, Yang Chen, Feng Pan, Zhi-Yong Wu, Jia-Sheng Zhang, Jian-Yi Wu, Xiu-E Xu, Jian-Mei Zhao, En-Min Li, Yi Zhao, Li-Yan Xu   +11 more
doaj   +1 more source

Redox Potentials of Disulfide Bonds in LOXL2 Studied by Nonequilibrium Alchemical Simulation

Frontiers in Chemistry, 2021
Lysyl oxidase-like 2 (LOXL2) is a metalloenzyme that catalyzes the oxidative deamination ε-amino group of lysine. It is found that LOXL2 is a promotor for the metastasis and invasion of cancer cells. Disulfide bonds are important components in LOXL2, and
Lirui Lin, Lirui Lin, Haiying Zou, Haiying Zou, Wenjin Li, Li-Yan Xu, Li-Yan Xu, En-Min Li, En-Min Li, Geng Dong, Geng Dong   +10 more
doaj   +1 more source

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

Nature Communications, 2021
The relevance and underlying molecular mechanisms of epigenetic regulation in squamous cell carcinomas (SCC) await further characterization. Here, the authors show a transcriptional regulatory loop involving SREBF1, TP63 and KLF5 driving tumourigenesis ...
Li-Yan Li, Qian Yang, Yan-Yi Jiang, Wei Yang, Yuan Jiang, Xiang Li, Masaharu Hazawa, Bo Zhou, Guo-Wei Huang, Xiu-E Xu, Sigal Gery, Ying Zhang, Ling-Wen Ding, Allen S. Ho, Zachary S. Zumsteg, Ming-Rong Wang, Melissa J. Fullwood, Stephen J. Freedland, Stephen J. Meltzer, Li-Yan Xu, En-Min Li, H. Phillip Koeffler, De-Chen Lin   +22 more
doaj   +1 more source

Increasing incidence of thyroid cancer in shanghai, China, 1983-2007 [PDF]

, 2011
Increasing incidences of thyroid cancer were observed in some countries, like USA, UK, France, etc. Jointpoint regression was used to analyze the incidence of thyroid cancer in Shanghai, China, from 1983 to 2007.
Wei Wang, Youxin Wang
core   +2 more sources

Prostate cancer incidence in Golestan province, Iran (2004) [PDF]

, 2008
Prostate cancer is the most common cancer in men and therefore represents a major problem in public health.The aim of this study was to find and evaluate province-specific estimate of incidence in males by age groups for prostate cancer in Golestan ...
Kabir, M.J., Marjani, A.
core   +1 more source

Cancer incidence in Behçet’s disease

Irish Journal of Medical Science (1971 -), 2020
e13583 Background: Previous studies demonstrated increased risk of cancer in systemic autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE) and sjögren syndrome due to uncontrolled inflammation. Behçet’s disease (BD) was also reported to be associated with an increased risk of cancer, although data is limited and ...
Deniz Can Guven, Ertugrul Cagri Bolek, Sabri Engin Altintop, Burcu Celikten, Burak Yasin Aktas, Sedat Kiraz, İbrahim Gullu, Omer Karadag, Omer Dizdar   +8 more
openaire   +3 more sources

Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC

Molecular Oncology, 2020
Long noncoding RNAs (lncRNAs) have important regulatory roles in cancer biology. Although some lncRNAs have well‐characterized functions, the vast majority of this class of molecules remains functionally uncharacterized.
Qiu‐Yu Wang, Liu Peng, Yang Chen, Lian‐Di Liao, Jia‐Xin Chen, Meng Li, Yan‐Yu Li, Feng‐Cui Qian, Yue‐Xin Zhang, Fan Wang, Chun‐Quan Li, De‐Chen Lin, Li‐Yan Xu, En‐Min Li   +13 more
doaj   +1 more source

L2Δ13, a splicing isoform of lysyl oxidase-like 2, causes adipose tissue loss via the gut microbiota and lipid metabolism

iScience, 2022
Summary: Obesity is primarily characterized by the dysregulation of lipid metabolism and gut microbiota. Here, we found that the body weight of transgenic mice overexpressing L2Δ13, a selectively spliced isoform of lysyl oxidase-like 2 (LOXL2), was lower
Yang Chen, Li-Xia He, Jin-Ling Chen, Xin Xu, Juan-Juan Wang, Xiu-Hui Zhan, Ji-Wei Jiao, Geng Dong, En-Min Li, Li-Yan Xu   +9 more
doaj   +1 more source

Lung cancer epidemiology in North Sardinia, Italy [PDF]

, 2013
Background The aim of this study was to analyze and describe the epidemiological characteristics and trends of lung cancer in North Sardinia, Italy, in the period 1992–2010.
Attene, Federico, Budroni, Mario, Cesaraccio, Rosaria, Cossu, Antonio, Paliogiannis, Panagiotis, Palmieri, Giuseppe, Tanda, Francesco, Trignano, Mario   +7 more
core   +1 more source

Does lowering the screening age for cervical cancer in The Netherlands make sense?\ud [PDF]

, 2008
Recommendations for the age to initiate cervical cancer screening should be directed towards maximum detection of early cervical cancer. However, the screening programme should do more good than harm. The aim of this analysis was to determine whether the
Anttila, Anttila, Arbyn, Arbyn, Arbyn, Barnabas, Bulk, Castle, de Graaf, de Sanjose, Engberts, Franco, Franco, Gustafsson, Haverkos, Jacobs, Kahn, Kyrgiou, Lahelma, Laukkanen, Loos, Miller, Mount, National Cancer Institute, Ostor, Raffle, Rebolj, Rebolj, Rogstad, Sigurdsson, Sigurdsson, Sinclair, Tacken, van Ballegooijen, van Ballegooijen, van Ballegooijen, Walboomers, Webb, Wilson   +38 more
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