Results 21 to 30 of about 1,083,547 (307)

Redox Potentials of Disulfide Bonds in LOXL2 Studied by Nonequilibrium Alchemical Simulation

Frontiers in Chemistry, 2021
Lysyl oxidase-like 2 (LOXL2) is a metalloenzyme that catalyzes the oxidative deamination ε-amino group of lysine. It is found that LOXL2 is a promotor for the metastasis and invasion of cancer cells. Disulfide bonds are important components in LOXL2, and
Lirui Lin, Lirui Lin, Haiying Zou, Haiying Zou, Wenjin Li, Li-Yan Xu, Li-Yan Xu, En-Min Li, En-Min Li, Geng Dong, Geng Dong   +10 more
doaj   +1 more source

Cancer incidence in Behçet’s disease

Irish Journal of Medical Science (1971 -), 2020
e13583 Background: Previous studies demonstrated increased risk of cancer in systemic autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE) and sjögren syndrome due to uncontrolled inflammation. Behçet’s disease (BD) was also reported to be associated with an increased risk of cancer, although data is limited and ...
Deniz Can Guven, Ertugrul Cagri Bolek, Sabri Engin Altintop, Burcu Celikten, Burak Yasin Aktas, Sedat Kiraz, İbrahim Gullu, Omer Karadag, Omer Dizdar   +8 more
openaire   +3 more sources

Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC

Molecular Oncology, 2020
Long noncoding RNAs (lncRNAs) have important regulatory roles in cancer biology. Although some lncRNAs have well‐characterized functions, the vast majority of this class of molecules remains functionally uncharacterized.
Qiu‐Yu Wang, Liu Peng, Yang Chen, Lian‐Di Liao, Jia‐Xin Chen, Meng Li, Yan‐Yu Li, Feng‐Cui Qian, Yue‐Xin Zhang, Fan Wang, Chun‐Quan Li, De‐Chen Lin, Li‐Yan Xu, En‐Min Li   +13 more
doaj   +1 more source

L2Δ13, a splicing isoform of lysyl oxidase-like 2, causes adipose tissue loss via the gut microbiota and lipid metabolism

iScience, 2022
Summary: Obesity is primarily characterized by the dysregulation of lipid metabolism and gut microbiota. Here, we found that the body weight of transgenic mice overexpressing L2Δ13, a selectively spliced isoform of lysyl oxidase-like 2 (LOXL2), was lower
Yang Chen, Li-Xia He, Jin-Ling Chen, Xin Xu, Juan-Juan Wang, Xiu-Hui Zhan, Ji-Wei Jiao, Geng Dong, En-Min Li, Li-Yan Xu   +9 more
doaj   +1 more source

Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features

Open Life Sciences, 2023
Clear cell renal cell carcinoma (ccRCC) is a major pathological type of kidney cancer with a poor prognosis due to a lack of biomarkers for early diagnosis and prognosis prediction of ccRCC.
Mo Yingxi, Zhao Jun, Zhao Ran, Huang Yiying, Liang Ziyuan, Zhou Xiaoying, Chu Jiemei, Pan Xinli, Duan Siyu, Chen Shiman, Mo Liufang, Huang Bizhou, Huang Zhaozhang, Wei Jiale, Zheng Qian, Luo Wenqi   +15 more
doaj   +1 more source

Cancer Incidence in Korea

Cancer Research and Treatment, 2002
We estimated the incidence of cancer in Korea.The indicence of cancer was estimated using national mortality data, and the incidence data from four frontier regional cancer registries, including Kangwha, Seoul, Busan and Deagu. These four registries served a population about seventeen million, which is almost 38% of entire population in Korea.The ...
Hai-Rim Shin, Yoon-Ok Ahn, Jong-Myon Bae, Myung-Hee Shin, Duk-Hee Lee, Choong-Won Lee, Heechoul Ohrr, Don-Hee Ahn, Jacques Ferlay, Dornald Maxwell Parkin, Dae-Kyu Oh, Jae-Gahb Park   +11 more
openaire   +2 more sources

Incidence trends in prostate cancer among men in the United States from 2000 to 2020 by race and ethnicity, age and tumor stage

Frontiers in Oncology, 2023
PurposeTo explore whether prostate cancer incidence trends from 2000 to 2020 in the United States differed by race and ethnicity, age and tumor stage; to explore racial differences in prostate cancer incidence change due to the impact of COVID-19 ...
Xianglin L. Du, Daoqi Gao, Zhuoyun Li
doaj   +1 more source

Lung cancer incidence and survival in different ethnic groups in South East England. [PDF]

, 2011
BACKGROUND: This study aimed to examine the incidence and survival of lung cancer patients from several different ethnic groups in a large ethnically diverse population in the United Kingdom.
Davies, E. A.; id_orcid, Jack, RH, Moller, H.; id_orcid, Møller, H, Davies, EA, H Møller, E A Davies, Jack, R. H., R H Jack   +8 more
core   +1 more source

Cancer incidence in the Falkland Islands [PDF]

British Journal of Cancer, 2001
Cancer incidence in the Falkland Islands, 1989-2000, was compared with rates in England and Wales, from which most Islanders originate. Colon and rectum cancer incidence was significantly raised 1989-93 but greatly reduced after 1994, when colonoscopic screening in high-risk families and sigmoidoscopic screening in the general population were ...
Swerdlow, AJ, Elsby, B, Qiao, Z
openaire   +3 more sources

CKD and the Risk of Incident Cancer [PDF]

Journal of the American Society of Nephrology, 2014
Previous studies report a higher risk of cancer in patients with ESRD, but the impact of less severe CKD on risk of cancer is uncertain. Our objective was to evaluate the association between level of kidney function and subsequent cancer risk. We performed a retrospective cohort study of 1,190,538 adults who were receiving care within a health care ...
William T, Lowrance, Juan, Ordoñez, Natalia, Udaltsova, Paul, Russo, Alan S, Go   +4 more
openaire   +2 more sources