Results 91 to 100 of about 5,208,219 (312)

Social interaction of cancer survivors in Malta : a sociological analysis [PDF]

open access: yes, 2016
This research analyzes social interaction of cancer patients in Malta. In particular it applies a qualitative sociological approach to verify how cancer patients interact with family members and society.
Briguglio, Michael, Tedesco, Charon
core  

Which interval is most crucial to presentation and survival in gastroesophageal cancer: a systematic review [PDF]

open access: yes, 2017
Aim: The aim of this study was to identify the most crucial interval to encourage earlier diagnosis in with gastroesophageal cancer and to identify potential factors effecting this interval.
Khulusi, Sam, Lee, Amanda, Watson, Roger
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Nanoformulation of Spirooxindole and Methods for Treating Hepatocellular Carcinoma

open access: yesPharmaceutics
Objectives: This in vivo study introduces a newly developed spirooxindole derivative that is deemed safe and effective as a potential targeted therapy for various cancers.
Assem Barakat   +6 more
doaj   +1 more source

Coordinating Summer Undergraduate Research Programs for Expanding Diversity and Impact: Opportunities and Challenges [PDF]

open access: yes, 2019
During summers 2015-2017, we operated a National Science Foundation (NSF) funded Research Experiences for Undergraduates (REU) Site, “Biomedical Engineering Community of Undergraduate Research Scholars for Cancer” (BME CUReS Cancer) at The University of ...
Cousins, Margo   +3 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Expert Consensus on the Clinical Application of PI3K/AKT/mTOR Inhibitors in the Treatment of Breast Cancer (2025 Edition)

open access: yesCancer Innovation
Background The phosphoinositide 3‐kinase (PI3K)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway (PAM pathway) plays a critical role in breast cancer pathogenesis and progression, and is closely linked with resistance ...
The Breast Cancer Expert Committee of the National Quality Control Center for Cancer   +3 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Last Year\u27s Virus, This Year\u27s Cancer Treatment [PDF]

open access: yes, 2018
For hundreds of years, cancer has stumped medical professionals across the world as a cure evaded them. Now, a new approach to battling cancer has entered the arena: viruses.
Collins, Olivia
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

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