Results 11 to 20 of about 23,836,233 (352)
Cancers, 2019 p21 functions as a cell cycle inhibitor and anti-proliferative effector in normal cells, and is dysregulated in some cancers. Earlier observations on p21 knockout models emphasized the role of this protein in cell cycle arrest under the p53 transcription factor activity.
Bahar Shamloo, Sinem Usluer
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Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
Molecular Cancer, 2023 The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental ...
Matin Chehelgerdi +13 more
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Big data in basic and translational cancer research
Nature Reviews. Cancer, 2022 Historically, the primary focus of cancer research has been molecular and clinical studies of a few essential pathways and genes. Recent years have seen the rapid accumulation of large-scale cancer omics data catalysed by breakthroughs in high-throughput
Peng Jiang +5 more
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Artificial Intelligence in Cancer Research and Precision Medicine.
Cancer Discovery, 2021 Artificial intelligence (AI) is rapidly reshaping cancer research and personalized clinical care. Availability of high-dimensionality datasets coupled with advances in high-performance computing, as well as innovative deep learning architectures, has led
B. Bhinder +3 more
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Applications of single-cell sequencing in cancer research: progress and perspectives
Journal of Hematology & Oncology, 2021 Single-cell sequencing, including genomics, transcriptomics, epigenomics, proteomics and metabolomics sequencing, is a powerful tool to decipher the cellular and molecular landscape at a single-cell resolution, unlike bulk sequencing, which provides ...
Ya-Nan Lei +7 more
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Spatial omics: Navigating to the golden era of cancer research
Clinical and Translational Medicine, 2022 The idea that tumour microenvironment (TME) is organised in a spatial manner will not surprise many cancer biologists; however, systematically capturing spatial architecture of TME is still not possible until recent decade.
Yingcheng Wu +4 more
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Applications of Microfluidics and Organ-on-a-Chip in Cancer Research
Biosensors, 2022 Taking the life of nearly 10 million people annually, cancer has become one of the major causes of mortality worldwide and a hot topic for researchers to find innovative approaches to demystify the disease and drug development.
Sagar Regmi +3 more
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Spatial transcriptomics technology in cancer research
Frontiers in Oncology, 2022 In recent years, spatial transcriptomics (ST) technologies have developed rapidly and have been widely used in constructing spatial tissue atlases and characterizing spatiotemporal heterogeneity of cancers.
Qichao Yu, Miaomiao Jiang, Liang Wu
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Recent Advances in Thyroid Cancer Research
International Journal of Molecular Sciences, 2022 This Special Issue (SI) "Recent Advances in Thyroid Cancer Research" covers research articles and reviews in the field of thyroid cancer research [...].
D. Grimm
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UK Biobank: a globally important resource for cancer research
British Journal of Cancer, 2022 UK Biobank is a large-scale prospective study with deep phenotyping and genomic data. Its open-access policy allows researchers worldwide, from academia or industry, to perform health research in the public interest.
Megan C. Conroy +12 more
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