Results 81 to 90 of about 25,337,422 (423)

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Humphrey Center News: Spring 1989 v. 4, no. 1 [PDF]

open access: yes, 1989
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University   +1 more
core  

The Cancer Research Campaign [PDF]

open access: yesCurrent Biology, 2000
Yes. David Lane, co-discoverer of the p53 tumour suppressor, and Mike Stratton, whose team identified and cloned the breast cancer susceptibility gene BRCA2, are two of the 1,300 scientists funded by the CRC.
openaire   +3 more sources

The World Cancer Research Fund/American Institute for Cancer Research Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: Impact and Future Directions.

open access: yesJournal of NutriLife, 2019
The Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: A Global Perspective by the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) represents the most comprehensive, detailed, and objective ...
S. Clinton, E. Giovannucci, S. Hursting
semanticscholar   +1 more source

Humanized Rodent Models for Cancer Research

open access: yesFrontiers in Oncology, 2020
As one of the most popular laboratory animal models, rodents have been playing crucial roles in mechanistic investigations of oncogenesis as well as anticancer drug or regimen discoveries.
H. Tian   +3 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling

open access: yesFrontiers in Physiology, 2012
Systems Biology holds that complex cellular functions are generated as system-level properties endowed with robustness, each involving large networks of molecular determinants, generally identified by omics analyses.
Lilia eAlberghina   +20 more
doaj   +1 more source

Longitudinal Position and Cancer Risk in the United States Revisited [PDF]

open access: yesarXiv, 2023
Background: The debate over daylight saving time has surged, with interests in the effects of sunlight exposure on health. \commentnj{Prior studies simulated daylight saving time and standard time conditions by analyzing different locations within time zones and neighboring areas across time zone borders.
arxiv  

Humphrey Center News: Fall 1987 v. 2, no. 2 [PDF]

open access: yes, 1987
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University   +1 more
core  

TOX3 mutations in breast cancer [PDF]

open access: yes, 2013
TOX3 maps to 16q12, a region commonly lost in breast cancers and recently implicated in the risk of developing breast cancer. However, not much is known of the role of TOX3 itself in breast cancer biology.
Caldas, Carlos   +6 more
core   +3 more sources

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