Results 91 to 100 of about 3,274,672 (298)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cancer-related fatigue presenting with excessive daytime sleepiness

SAGE Open Medical Case Reports, 2017
Cancer-related fatigue is a common symptom in cancer patients which commonly occurs in relation to sleep disturbance. We report a case of a 35-year-old breast cancer survivor, in whom polysomnography and multiple sleep latency testing were utilized to ...
Diwakar D Balachandran, Saadia A Faiz, Lara Bashoura, Ellen Manzullo   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Delaware Cancer Survivor Work Optimization Needs Assessment

, 2020
Every year, over 5,600 working-age Delawareans are affected by cancer. Maintaining health insurance and a sense of normalcy are two of the primary reasons that cancer survivors continue or return to work following treatment.
O'Dell, Catharine Lee.
core  

Health care use of long-term survivors of childhood cancer: the British Childhood Cancer Survivor Study [PDF]

, 2011
Purpose Survivors of childhood cancer are at high risk of chronic conditions, but few studies investigated whether this translates into increased health care utilization.
Lancashire, Emma R, Toogood, Andrew, David L. Winter, Frobisher, Clare, Kuehni, CE, Reulen, Raoul; id_orcid, Rebholz, Cornelia E, Clare Frobisher, Raoul C. Reulen, Hawkins, Michael, Andrew A. Toogood, Winter, David L, Hawkins, Michael M, Lancashire, Emma, Michael M. Hawkins, Winter, David, Reulen, Raoul C, Kuehni, Claudia E, Claudia E. Kuehni, Frobisher, Clare; id_orcid, Emma R. Lancashire, Toogood, Andrew A, Rebholz, Cornelia, Cornelia E. Rebholz   +23 more
core   +1 more source

Other Title: Cancer Prevention and Control Plan 2017-2021

, 2017
"The Kansas Cancer Prevention and Control Plan is a road map for addressing cancer in the following ways: Addresses issues common across all cancers and highlights cancers with the highest incidence and mortality in Kansas.
Kansas Cancer Partnership.
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The isolation of cancer survivors [PDF]

European Journal of Cancer Care, 2020
Giada Danesi, Céline Bourquin, Friedrich Stiefel, Khalil Zaman, Michael Saraga   +4 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source